Results 81 to 90 of about 9,633,208 (257)
Switching the human-power back on: domesticating human-power to practice energy saving behaviour [PDF]
, 2014 This research took an exploration into particular products which use human-power as main power source. Against the problem of over consumption of energy, it views the ‘human-powered product’ (HPP) not merely as an object that simply generates ‘free ...
Shin, HD
core
An agent-based model of the female rivalry hypothesis for concealed ovulation in humans.
, 2022 After half a century of debate and few empirical tests, there remains no consensus concerning why ovulation in human females is considered concealed.
Claessens, Scott +5 more
core +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Child and Adolescent Psychiatry and Mental HealthBackground CLP is a complex congenital anomaly with considerable psychosocial and medical implications. Despite recognised psychiatric co morbidity, mental health integration in cleft services remains uncommon in LMICs. This study prospectively evaluated
Ajay Aditya Aadhi Mani, Aksha Gaunekar
doaj +1 more source
Research on the welfare of pet guinea pigs and connections between their behaviour and husbandry practices is scarce. Through an online survey among 1181 German-speaking guinea pig caretakers, we investigated husbandry practices (including social ...
Ines Windschnurer +5 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Biochemistry and Biophysics ReportsNeurology research largely utilizes rat brains due to their structural and functional similarities to humans, making them valuable models for studying various neurological conditions.
Pratibha Sharma, Rajinder K. Dhamija
doaj +1 more source
Developing a university-wide academic integrity E-learning tutorial: a Canadian case
International Journal for Educational Integrity, 2019 Academic integrity has become a significant point of concern in the post-secondary landscape, and many institutions are now exploring ways on how to implement academic integrity training for students.
Lyle Benson +3 more
doaj +1 more source