Engaging with Socio-Economically Disadvantaged Communities and Their Cats: Human Behaviour Change for Animal and Human Benefit. [PDF]
Animals (Basel), 2019 McDonald JL, Clements J.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Better Lives for Dogs: Incorporating Human Behaviour Change Into a Theory of Change to Improve Canine Welfare Worldwide. [PDF]
Front Vet Sci, 2018 Reed K, Upjohn MM.
europepmc +1 more source
Behavioural change as the core of warfighting : So now what?
, 2017 This article focuses on understanding human behaviour by providing an insight into its underlying mechanisms, and aims to widen the view on the military possibilities for achieving mission goals.
Boor, R.A.E. van der +3 more
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Cognitive biases, heuristics and decision-making in design for behaviour change [PDF]
, 2012 Copyright @ 2012 Social Science Electronic PublishingMuch human behaviour can be seen as decision-making, and so understanding and influencing those decision-making processes could be an important component in design for behaviour change.
Lockton, D
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Human Behaviour-Change Project: harnessing the power of artificial intelligence and machine learning for evidence synthesis and interpretation. [PDF]
Implement Sci, 2017 Michie S +11 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Amicus Brief – Human Rights and Climate Change
, 2017 Submission made by the Asia Pacific Forum of National Human Rights Institutions and the Global Alliance of National Human Rights Institutions (GANHRI) in support of a petition by Greenpeace Southeast Asia and the Philippine Rural Reconstruction Movement ...
Hartmann, Jacques; id_orcid +3 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source