Results 121 to 130 of about 10,397,260 (306)
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The article analyzes activities of the Administration of Federal Service for Surveillance on Consumer Rights Protection and Human Well-being in Khabarovsky Krai and the Federal Health Organization "Center of Hygiene and Epidemiology in Khabarovsky Krai ...
V. A. Ott +9 more
doaj
Relevance. It is known that the immune response to the administration of immunobiological drugs is variable and depends on the individual characteristics of the organism.
N. V. Vlasenko +9 more
doaj +1 more source
A balance between putting on the researcher's hat and being a fellow human being: a researcher perspective on informal carer involvement in health and social care research. [PDF]
Malm C +3 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The spread of Vibrio cholerae strains with multiple antibiotic resistances makes it necessary to search for alternative antibiotics that are effective against the cholera pathogen.
A. V. Tyurina +6 more
doaj
The EU's Hospitality and Welcome Culture: Conceiving the "No Human Being Is Illegal" Principle in the EU Fundamental Freedoms and Migration Governance. [PDF]
Aliu A, Aliu D.
europepmc +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The Sufferings of the Biblical Job as an Icon of Postmodernity: The 'loneliness' of God and the human being in a consumerist paradise. [PDF]
Stala J, Osewska E, Bochenek K.
europepmc +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

