Results 211 to 220 of about 24,686,030 (394)

Ecosystem effects on well-being: More than just "benefits"? Looking at ecosystem services through the capability approach [PDF]

open access: yes
Conceptual discussions on the impacts of ecosystem services (ESS) on human well-being have largely been boiled down to limits and applications of their monetisation.
Polishchuk, Yuliana, Rauschmayer, Felix
core  

Correction: Past and current status of adolescents living with HIV in South Africa, 2005–2017

open access: yesBMC Research Notes
Inbarani Naidoo   +9 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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