Results 141 to 150 of about 2,100,730 (306)

A Core-Shell Au@TiO₂ and Multi-Walled Carbon Nanotube-Based Sensor for the Electroanalytical Determination of H₂O₂ in Human Blood Serum and Saliva. [PDF]

Biosensors (Basel), 2022
Saeed AA, Abbas MN, El-Hawary WF, Issa YM, Singh B.   +4 more
europepmc   +1 more source

Toward a Human Blood Serum Proteome [PDF]

Molecular & Cellular Proteomics, 2002
Joshua N. Adkins, Susan M. Varnum, Kenneth J. Auberry, Ronald J. Moore, Nicolas H. Angell, Richard D. Smith, David L. Springer, Joel G. Pounds   +7 more
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors

Frontiers in Cell and Developmental Biology
IntroductionThe changing composition of non-cell autonomous circulating factors in blood as humans age is believed to play a role in muscle mass and strength loss.
Sin-Ruow Tey, Ryan S. Anderson, Clara H. Yu, Samantha Robertson, Heidi Kletzien, Heidi Kletzien, Nadine P. Connor, Nadine P. Connor, Kaori Tanaka, Yasuyuki Ohkawa, Masatoshi Suzuki, Masatoshi Suzuki, Masatoshi Suzuki   +12 more
doaj   +1 more source

Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach. [PDF]

Clin Proteomics, 2021
Serrano-Blesa E, Porter A, Lendrem DW, Pitzalis C, Barton A, Treumann A, Isaacs JD.   +6 more
europepmc   +1 more source

Predicting Prostate Cancer Aggressiveness through a Nanoparticle Test [PDF]

, 2011
Prostate cancer (PCa) is the most common malignancy and the second leading cause of cancer death in American men. Due to the lack of accurate tests to distinguish aggressive cancer from indolent tumor, prostate cancer is often over-treated.
David Decker, Hillari Hallquist, Inoel Rivera-Ramirez, Qun Huo, Sally Litherland, Shannon Sullivan   +5 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Analysis of the Increase of Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression and the Effect of Exposure in a Hyperbaric Chamber on VCAM-1 in Human Blood Serum: A Cross-Sectional Study. [PDF]

Medicina (Kaunas), 2022
Van Damme-Ostapowicz K, Cybulski M, Kozakiewicz M, Krajewska-Kułak E, Siermontowski P, Sobolewski M, Kaczerska D.   +6 more
europepmc   +1 more source