Results 151 to 160 of about 2,587,341 (268)

Anatomy at the threshold: Teaching the human body in a hybrid age. [PDF]

Anat Sci Educ
Cortese K, Falletta P.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Visualization of Medical Record with 3D Human Body Models. [PDF]

Healthcare (Basel)
Liu TJ, Lai CY, Chiang YC.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Tracing Microplastics in the Human Body: From Detection to Disease Mechanisms. [PDF]

Diagnostics (Basel)
Talau SA, Chialda M, Ichim C, Dura H, Tanasescu C.   +4 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Miniaturized olfactory sensor chip-based AI-wearable biometric ring for human body metabolic odor analysis. [PDF]

Nat Commun
Ye W, Ding R, Wang C, Tang W, Zhang D, Qiu X, Poddar S, Wan Z, Chan CLJ, Xue F, Fu Y, Ren B, Wang B, Zhou Y, Long Z, Ding Y, Zhang W, Wan Z, Zhao J, Lin Y, Fan Z.   +20 more
europepmc   +1 more source

The Human Body [PDF]

American Journal of Public Health and the Nations Health, 1947
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Medical importance and pharmacokinetics of gold nanoparticles in the human body. [PDF]

Mol Cancer
Singh P, Joshi AS, Singh H, Mijakovic I.
europepmc   +1 more source