Results 81 to 90 of about 7,725,142 (285)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Ultrasonic properties of human bones in senile osteoporosis
Acta Orthopaedica et Traumatologica Turcica, 2021 Biomechanical properties of the femoral heads of six cases with osteoporosis who underwent hip surgery were investigated by ultrasonic methods. Ultrasonic velocities and moduli of elasticity in the tangential, radial and axial directions were determined ...
Yener Nail Yeni +3 more
doaj
Sex and side determination of human hip bone by metric parameters of its posterior border
National Journal of Clinical Anatomy, 2013 Background: Identification of sex from skeletal remains is of medico-legal and anthropological importance for forensic experts, anthropologists and anatomists.
Sarita R Margam +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
An Anthropological Evaluation on Fluorosis
Van Tıp Dergisi, 2019 Fluorine is found in nature in fluorine compounds and is a trace element in human body. Fluorine is found in water sources, soils, rocks, food and drinks and incorporated into structure of our skeleton and teeth.
Seda Karaöz Arıhan, Ramazan Türkekul
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
The human-dog relationship in early medieval England and Ireland (c. AD 400-1250)
, 2012 This thesis aims to explore the human-dog relationship in early medieval England and Ireland (c. AD 400-1250) and so develop an improved understanding of how people perceived and utilised their dogs.
Grieve, Amanda
core +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source