Results 151 to 160 of about 801,707 (316)

Osteocalcin in human breast milk over the course of lactation. [PDF]

Front Endocrinol (Lausanne)
Prosperi O, Hanusch B, Naber S, Lücke T, Sinningen K.   +4 more
europepmc   +1 more source

Progesterone receptor replenishment in T47D human breast cancer cells. Roles of protein synthesis and hormone metabolism.

, 1983
Kathryn B. Horwitz, Mary B. Mockus, Adrian W. Pike, Paul V. Fennessey, Robert L. Sheridan   +4 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

HCCS Serves as Potential Prognostic Biomarker and Therapeutic Target in Human Breast Cancer. [PDF]

Int J Breast Cancer
Bellah SF, Hossen MA, Billah SMS, Islam MN.   +3 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Cell populations in human breast cancers are molecularly and biologically distinct with age. [PDF]

Nat Aging
Parsons A, Sauras Colón E, Manjunath M, Zhang H, Chen J, Spasic M, Koca B, Binboga Kurt B, Freedman RA, Mittendorf EA, Swarbrick A, van Galen P, McAllister SS.   +12 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Differential effects of minocycline on human breast epithelial cells, human breast cancer cells and their tumor hybrids. [PDF]

Mol Biol Rep
Moayed F, Keil S, Dittmar T, Weiler J.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Microbiome Profiling of Pretreated Human Breast Milk Using Shotgun Metagenomic Sequencing. [PDF]

J Microbiol Biotechnol
Zhang Q, Zhang Y, Zhu J, Gao Y, Zeng W, Qi H.   +5 more
europepmc   +1 more source