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Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones.

Cell Rep
Nguyen LV, Eyal-Lubling Y, Guerrero-Romero D, Kronheim S, Chin SF, Manzano Garcia R, Sammut SJ, Lerda G, Lui AJW, Bardwell HA, Greenwood W, Shin HJ, Masina R, Kania K, Bruna A, Esmaeilishirazifard E, Kolyvas EA, Aparicio S, Rueda OM, Caldas C.   +19 more
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Human breast development

Seminars in Cell & Developmental Biology, 2012
This review is intended to give an overview of current knowledge on human breast development. It focuses on the limitations of our understanding on the origins of human breast cancer in the context of this mainly morphological and static assessment of what is known about human breast development.
Barry A, Gusterson, Torsten, Stein
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Human Breast Development

Journal of Mammary Gland Biology and Neoplasia, 2000
This review presents an atlas of the histology of the normal physiological states of the human breast including prenatal, prepubertal, and pubertal development, adult resting gland, pregnancy, lactation, and postinvolution. The aim is to produce a pictorial overview of the main stages in development and the common findings in the adult that are ...
B A, Howard, B A, Gusterson
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Peripubertal human breast development

The Anatomical Record, 1990
AbstractThe microanatomical and histological appearance of the human breast has been studied during puberty. The macroscopic architecture of the mammary epithelial tree was identified and correlated with the histological appearance of material excised from defined regions of the breast preparations. Between ages 13 yrs and 15 yrs the human breast shows
P, Monaghan, N P, Perusinghe, P, Cowen, B A, Gusterson   +3 more
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Steroids and human breast cancer

Journal of Steroid Biochemistry, 1975
Abstract Estrogen receptor is present in the rat in target tissues, including mammary gland and hormone dependent mammary tumors, but is absent in non-target tissues and in many autonomous tumors. In human tissues, estrogen receptor behaves much like that of the rat.
W L, McGuire, G C, Chamness, M E, Costlow, N J, Richert   +3 more
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Synaptophysin in human breast carcinomas

Histopathology, 1991
Synaptophysin expression was studied immunohisto‐chemically in 109 female and in three male breast carcinomas. Positivity was demonstrated in 10 female and in two male tumours in a high percentage of neoplastic cells. Synaptophysin positive breast carcinomas also expressed other neuroendocrine markers such as chromogranin and neuron‐specific enolase.
UCCINI, Stefania, F. Monardo, P. Paradiso, R. Masciangelo, A. Marzullo, RUCO, Luigi, C. D. Baroni   +6 more
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Androgens in human breast carcinoma

Medical Molecular Morphology, 2010
Sex steroids play important roles in the development of human breast carcinoma. Androgen receptor (AR) is expressed in a majority of breast carcinoma tissues. However, the significance of androgen actions remains largely unclear in breast carcinoma, differing from estrogen actions. Therefore, in this review, we summarized recent studies on androgens in
Takashi, Suzuki, Yasuhiro, Miki, Kiyoshi, Takagi, Hisashi, Hirakawa, Takuya, Moriya, Noriaki, Ohuchi, Hironobu, Sasano   +6 more
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Aluminium and human breast diseases

Journal of Inorganic Biochemistry, 2011
The human breast is exposed to aluminium from many sources including diet and personal care products, but dermal application of aluminium-based antiperspirant salts provides a local long-term source of exposure. Recent measurements have shown that aluminium is present in both tissue and fat of the human breast but at levels which vary both between ...
P. D. Darbre, D. Pugazhendhi, MANNELLO, FERDINANDO   +2 more
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