Results 231 to 240 of about 11,937,554 (392)

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

open access: yesAdvanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao   +6 more
wiley   +1 more source

Skill dependencies uncover nested human capital. [PDF]

open access: yesNat Hum Behav
Hosseinioun M   +3 more
europepmc   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

Genetic disparities in sleep traits and human capital development: A 25-year study in Finnish population-based cohorts. [PDF]

open access: yesScand J Work Environ Health
Hazak A   +8 more
europepmc   +1 more source

Polarization‐Dependent 3D Holography Generated by Inverse Design Nanoprinting Metasurface

open access: yesAdvanced Science, EarlyView.
A novel polarization‐dependent 3D holography is proposed by introducing polarization as an additional freedom, enabling enhanced depth selectivity and greater control over holographic reconstruction. The efforts perfectly combine the polarization and 3D holography display into ADAM gradient descent algorithm, the application of nanoprinting further ...
Lingxing Xiong   +7 more
wiley   +1 more source

Aging and urban innovation: a human capital perspective. [PDF]

open access: yesFront Public Health
Cui J   +5 more
europepmc   +1 more source

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