Results 51 to 60 of about 9,965,276 (342)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Education today is not simple nor does it occur in isolation. Educators, now more than ever, are teaching within the global context of calls to action for truth and reconciliation with Indigenous communities around the world and a growing awareness of ...
Margaret MacDonald
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The construction industry is undergoing a paradigm shift with the advent of Construction 5.0 (C5.0), which integrates artificial intelligence (AI), the Internet of Things (IoT), digital twins, blockchain, and robotics to enhance productivity ...
Mahdi Akhavan +6 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Client-centricity and clientocracy: evolution of approaches in public administration
Transformation of approaches to public administration has an increasing tendency of using successful entrepreneurial experience proven by long-term practice in the market.
V. Yu. Razgulyaev +2 more
doaj +1 more source
eIDeCert: a user-centric solution for mobile identification [PDF]
The necessity to certify one's identity for different purposes and the evolution of mobile technologies have led to the generation of electronic devices such as smart cards, and electronic identities designed to meet daily needs.
Argles, David +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Qualitative analysis of academic group and discussion forum on Facebook [PDF]
In the present study, data was triangulated and two methods of data analysis were used. Qualitative analysis was undertaken of free-text data from students’ reflective essaysto extract socially-related themes. Heuristic evaluation was conducted by expert
Arendt, Dr Hannah +2 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

