Results 81 to 90 of about 9,965,276 (342)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Into the Revolution of Industry 5.0 in Ensuring Ethical Fashion: A Review on Conceptual Framework

Tekstilec
The global fashion industry faces numerous ethical concerns. The Global South, in particular, suffers from unethical practices in the fashion industry due to the complexity of the supply chain and the lack of regulations governing workers’ welfare ...
Shah Md. Maruf Hasan, Md. Nahid-Ull- Islam   +1 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Use of Artificial Intelligence (AI) in the Workplace Ergonomics of Industry 5.0

Tehnički Glasnik
Industry 5.0 emphasizes human-centricity, sustainability, and resilience as its core characteristics, with a focus on developing socio-technical systems that enhance human health, safety, and well-being while fostering sustainable societal practices. The
Maja Trstenjak, Tihomir Opetuk, Goran Đukić, Hrvoje Cajner   +3 more
doaj   +1 more source

The effect of organizational culture on CRM success [PDF]

, 2013
Copyright @ 2013 EMCIS.The aim of this paper is to develop a theoretical framework exemplifying the effect of organizational culture on the success of Customer Relationship Management (CRM) systems' implementation.
Al Duwailah, F, Ali, M
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Visual attributes of subliminal priming images impact conscious perception of facial expressions [PDF]

, 2019
We investigated, in young healthy participants, how the affective content of subliminally presented priming images and their specific visual attributes impacted conscious perception of facial expressions.
Huang, Melissa A., Sun, Hsin-Mei, Vaina, Lucia M.   +2 more
core  

How do enterprises respond to a managerial accounting performance measure mandated by the state? [PDF]

, 2017
We study the application of Economic Value Added (EVA®) by Chinese state-owned enterprises (SOEs) following a regulatory requirement to deploy the measure.
Alnoor Bhimani, Andon, Beckert, Bovens, Brandsma, Canning, Chen, Chen, Chen, Chen, Covaleski, Covaleski, DiMaggio, Du, Duh, Eisenhardt, Elster, Ezzamel, Fan, Firth, Firth, Firth, Firth, Fogarty, Greenwood, Guliang Tang, Haniffa, Hayne, Holm, Huang, Ke, Klenk, Kraatz, Lawrence, Lawrence, Lawrence, Lawrence, Lei, Lounsbury, Lu, Malsch, Mensah, Meyer, Mok, Mol, Moore, Narisa Tianjing Dai, O'Connor, Oliver, Perkmann, Prabhu Sivabalan, Scott, Scott, Selznick, Seo, Sharma, Suchman, Suddaby, Suddaby, Tolbert, Tu, Verbeeten, Wu, Young, Zietsma   +64 more
core   +1 more source

Unravelling human-centric tensions towards Industry 5.0: Literature review, resolution strategies and research agenda

Digital Business
In recent years, heightened attention has been directed towards the emerging Industry 5.0 (I5.0) paradigm, advocating intelligent collaboration between human workers and machines to enhance efficiency, productivity, customization, and product quality in ...
Diego A. de J. Pacheco, Bartosz Iwaszczenko   +1 more
doaj   +1 more source