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Human chorionic gonadotropin tests
Expert Review of Molecular Diagnostics, 2009Human chorionic gonadotropin (hCG) is not a single biological molecule. There is the regular form of hCG produced by differentiated syncytotrophoblast cells (regular hCG). This hormone primarily functions to maintain the myometrial and decidual spiral arteries, or the vascular supply of the placenta during the full course of pregnancy ...
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Determination of human chorionic gonadotropin
Best Practice & Research Clinical Endocrinology & Metabolism, 2013Determination of human chorionic gonadotropin (hCG) is used for diagnosis and monitoring of pregnancy, pregnancy related disorders, for trophoblastic and some nontrophoblastic tumors. In addition, hCG is determined for doping control in males. Assay of hCG is complicated by the occurrence of different molecular forms, which are detected to various ...
Alfthan Henrik +3 more
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Human chorionic gonadotropin in cancer
Clinical Biochemistry, 2004Human chorionic gonadotropin (hCG) is mainly used for detection and monitoring of pregnancy and pregnancy-related disorders but it is also an extremely sensitive and specific marker for trophoblastic tumors of placental and germ cell origin. Thus treatment of relapsing choriocarcinomas and testicular germ cell tumors is often initiated on the basis of ...
Ulf-Håkan, Stenman +2 more
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Radioimmunoassay for human chorionic gonadotropin
American Journal of Obstetrics and Gynecology, 1968Abstract A radioimmunoassay method for HCG utilizing I 125 for iodination and a chemical procedure for separation of free and bound HCG 125 are described. This method is more sensitive and more accurate than the hemagglutination inhibition technique.
Y, Tomoda, M M, Hreshchyshyn
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Withholding Gonadotropins Until Human Chorionic Gonadotropin Administration
Seminars in Reproductive Medicine, 2010Withholding gonadotropins in women who exhibit high estradiol responses before follicles reach full maturation is called "coasting." Coasting, or suspending gonadotropin administration, can be an effective strategy for decreasing the risk of ovarian hyperstimulation syndrome (OHSS) while reducing cancelation rates.
Rony, Abdallah +3 more
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Immunocytochemistry of human chorionic gonadotropin in human chorionic villi
American Journal of Obstetrics and Gynecology, 1987The immunocytochemical localization of human chorionic gonadotropin was investigated in chorionic villi from the seventh to twelfth week of gestation. By the light microscopic peroxidase-antiperoxidase technique, positive reactions of human chorionic gonadotropin were found exclusively in the syncytiotrophoblast.
K, Hamasaki +4 more
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Human chorionic gonadotropin in commercial human menopausal gonadotropin preparations
Fertility and Sterility, 1993Several studies indicated the presence of an hCG-immunoreactive substance in commercial hMG preparations. Because hCG represents LH activity with a relatively very long half-life, differences between hMG preparations with respect to hCG content could imply clinical differences.
P G, Stokman +5 more
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Studies of Human Chorionic Gonadotropin
1971Publisher Summary This chapter focuses on human chorionic gonadotropin (HCG), a glycoprotein hormone produced by the placenta that appears in significant quantities in the urine during the first trimester of pregnancy. The mean level of urinary HCG produced during the first trimester is 30,000–50,000 IU in 24 hours, equivalent to a maximum of ...
R E, Canfield +4 more
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Human chorionic gonadotropin-secreting osteosarcoma
BMJ Case ReportsSecretion of beta human chorionic gonadotropin (β-hCG) is a rare, recently recognised paraneoplastic syndrome. Herein, we present a case of a woman in her 30s with right femur conventional high-grade osteosarcoma and a positive screening urine pregnancy test. Subsequent workup failed to reveal an intrauterine or extrauterine pregnancy.
Natalia Gabriela Sanchez +3 more
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Immunochemistry of Human Chorionic Gonadotropin
1984In states of gestational trophoblastic disease, knowledge of the immunochemistry of human chorionic gonadotropin (hCG) is principally of value in relation to its use as a diagnostic tool and as a marker for the persistence of disease activity during chemotherapy (1, 2).
R E, Canfield +3 more
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