Results 301 to 310 of about 76,840 (343)
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Human chorionic gonadotropin and malignant mesothelioma
Cancer, 1979A 56-year-old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had ...
S, Rich +4 more
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Biosynthesis of Human Chorionic Gonadotropin*
Endocrine Reviews, 1980HUMAN chorionic gonadotropin (hCG) is a glycoprotein hormone normally secreted by trophoblastic cells of the placenta during pregnancy. Trophoblastic tumors and some nontrophoblastic tumors also secrete hCG and/or its α- or β-subunit. This review emphasizes a number of aspects, some controversial, of hCG biosynthesis and secretion that have received ...
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Carboxypeptidase Digestion of Human Chorionic Gonadotropin
Endocrine Research Communications, 1977Native human chorionic gonadotropin (hCG) was resistant to carboxypeptidase digestion even in the presence of urea. Isolated alpha subunit of the hormone (hCG-alpha), though unreactive to enzyme treatment in the absence of denaturant, released up to four amino acid residues from the C-terminus on incubation with a mixture of carboxypeptidases A and B ...
V G, Hum, H G, Botting, K F, Mori
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Thyrotropic Action of Human Chorionic Gonadotropin
Thyroid, 1995Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors. In these cases, greatly increased human chorionic gonadotropin (hCG) levels and suppressed TSH levels suggest that hCG has thyrotropic activity.
M, Yoshimura, J M, Hershman
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Antibodies to human chorionic gonadotropin in humans
Clinica Chimica Acta, 1981Very few observations have been published about the development of antibodies against gonadotropins in the human. Human FSHand hCG-antibodies have been detected in a patient with isolated FSH-deficiency after human menopausal gonadotropin administration [l], or after human menopausal (hMG) and chorionic gonadotropin (hCG) administration in women with ...
K, Musch, A S, Wolf, C, Lauritzen
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Human chorionic gonadotropin in pregnancy diagnostics
Clinica Chimica Acta, 2011Human chorionic gonadotropin (hCG) is a 237 aminoacid glycoprotein hormone composed of two dissimilar α and β subunits noncovalently linked by charge interactions, which are both required for the biological activity of the hormone. Due to structural heterogeneity, hCG exists in biological fluids as a mixture of different isoforms, i.e., intact active ...
MONTAGNANA, Martina +4 more
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Human chorionic gonadotropin and associated molecules
Expert Review of Molecular Diagnostics, 2009When considering human chorionic gonadotropin (hCG) and hCG tests, it is important to realize that it is not a single biological molecule. The regular form of hCG produced by differentiated syncytotrophoblast cells (regular hCG) is a hormone made with the primary function of maintaining the myometrial and decidual spiral arteries and the vascular ...
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Inherited human chorionic gonadotropin.
The Journal of reproductive medicine, 2010To investigate 405 cases of persistent low concentrations of human chorionic gonadotropin (hCG).The USA hCG Reference Service measured total regular hCG, follicle stimulating hormone and luteinizing hormone (LH) with the Siemens (New York, New York) Immulite 1000 assay. Hyperglycosylated hCG, nicked hCG, C-terminal peptide total hCG, intact regular hCG,
Laurence A, Cole, Laura L, Laidler
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