Results 301 to 310 of about 72,892 (336)

Crystal structure of human chorionic gonadotropin

Nature, 1994
The three-dimensional structure of human chorionic gonadotropin shows that each of its two different subunits has a similar topology, with three disulphide bonds forming a cystine knot. This same folding motif is found in some protein growth factors. The heterodimer is stabilized by a segment of the beta-subunit which wraps around the alpha-subunit and
K. J. Machin, J. W. Lustbader, R. E. Canfield, Neil W. Isaacs, Adrian J. Lapthorn, Allison Littlejohn, F. J. Morgan, D. C. Harris   +7 more
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Radioreceptor Assay for Human Chorionic Gonadotropin

The Journal of Clinical Endocrinology & Metabolism, 1975
A sensitive radioreceptor assay capable of detecting 100 pg of human chorionic gonadotropin has been developed using ovarian receptors and (125I)hCG. The dose-response curves of a series of urine and serum samples from pregnant women were linear and parallel to standard curves of 2nd International Standard hCG and purified hCG when logit of percent ...
C. Y. Lee, Robert J. Ryan
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Immunology of Human Chorionic Gonadotropin (HCG)

1967
Publisher Summary This chapter discusses the immunology of human chrionic gonadotropin (HCG). It also reviews the immunology of HCG, examples of various disciplines involved in hormone research where immunological methods are employed. These include the characterization of HCG preparations, the detection of contaminating proteins, quantitative ...
B. Lunenfeld, Aliza Eshkol
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Depyrogenation of Human Chorionic Gonadotropin

1980
Using ultrafiltration, the successful removal of endogenous pyrogens from a complex glycoprotein (molecular wieght = 59,000) has been achieved. Several lots of lyophilized human chorionic gonadotropin were pyrogenic, according to the official USP Rabbit Pyrogen Test.
David S. Johnson, Bernard LePage, Edward Fitzgerald, Karl Lin   +3 more
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Tissue distribution of human chorionic gonadotropin

American Journal of Obstetrics and Gynecology, 1970
Abstract Tissue distribution of exogenous HCG was studied in adult female mice injecting the animals with HCG-I 125 , BSA-I 125 , and I 125 and determining in a scintillation counter the tissue radioactivity at various time intervals. The radioactive materials were extracted from the tissues and mixed with excess anti-HCG serum. It was found that the
S. Kazeto, Myroslaw M. Hreshchyshyn
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Human chorionic gonadotropin and associated molecules

Expert Review of Molecular Diagnostics, 2009
When considering human chorionic gonadotropin (hCG) and hCG tests, it is important to realize that it is not a single biological molecule. The regular form of hCG produced by differentiated syncytotrophoblast cells (regular hCG) is a hormone made with the primary function of maintaining the myometrial and decidual spiral arteries and the vascular ...
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Human Chorionic Gonadotropin

Seminars in Reproductive Medicine, 1992
Song-Guang Ren, Glenn Braunstein
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The primate placenta and human chorionic gonadotropin

Experimental and Clinical Endocrinology & Diabetes, 2009
In the primate placenta various peptide and proteohormones are synthesized which control growth and development of the fetus as well as the exchange of nutrients and metabolic products between the mother and the fetus. In humans, maintenance of pregnancy in the first trimester depends on the synthesis of the bioactive glycoprotein hormone human ...
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Human Chorionic Gonadotropin Assays and Their Uses

Obstetrics and Gynecology Clinics of North America, 1988
The successful treatment of gestational trophoblastic disease has been partially achieved because of the ability to quantitate serum or urinary concentrations of human chorionic gonadotropin (hCG). Thus, the hCG assay has become essential to the clinical management of trophoblastic disease.
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Human chorionic gonadotropin hormone is antiviral

Medical Hypotheses, 1996
Although it is well known that human chorionic gonadotropin maintains the corpus luteum's ability to secrete estrogen and progesterone, I believe that it serves yet another important function. Early evidence suggests that human chorionic gonadotropin is a broad-spectrum antiviral/immune potentiator.
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