Results 101 to 110 of about 19,354 (212)
Feasibility of a cryopreservation of cultured human corneal endothelial cells
PLoS ONE, 2019 Transparency of the cornea is essential for vision and is maintained by the corneal endothelium. Consequently, corneal endothelial decompensation arising from irreversible damage to the corneal endothelium causes severe vision impairment. Until recently,
Naoki Okumura +5 more
semanticscholar +1 more source
Denudation of human amniotic membrane by a novel process and its characterisations for biomedical applications [PDF]
, 2016 This study was aimed to investigate the suitability of a modified method to get decellularised human amniotic membrane (DHAM). The obtained membrane was subjected to physico-chemical and biological evaluations to validate its potential for biomedical ...
R. Kumar, R. Sripriya
core +1 more source
The role of dinucleoside polyphosphates on the ocular surface and other eye structures [PDF]
, 2016 Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present
Carracedo Rodríguez, Juan Gonzalo +3 more
core +1 more source
P27 Expression in Endothelin-1 Stimulated Mitogenesis [PDF]
, 2007 Bovine corneal endothelial cells (BCECs) have been shown in our lab to synthesize and secrete endothelin-1 (ET-1). The endothelin-1 binds ETA receptors, this elevates intracellular calcium, stimulate DNA replication and cell division.
Kiriu, Joseph
core +1 more source
Investigative Ophthalmology and Visual Science, 2017 Purpose We have begun a clinical trial of a cell-based therapy for corneal endothelial dysfunction in Japan. The purpose of this study was to investigate the usefulness of a p38 MAPK inhibitor for prevention cellular senescence in cultivated human ...
Akane Hongo +4 more
semanticscholar +1 more source
Scientific Reports, 2017 Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha +3 more
semanticscholar +1 more source
Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon [PDF]
, 2008 Growth factors and their respective receptors are key regulators in development and homeostasis of the nervous system, and changes in the function, expression, or downstream signaling of growth factors are involved in many neuropathological disorders ...
Alon +65 more
core +2 more sources
Investigative Ophthalmology and Visual Science, 2017 Purpose Cultured human corneal endothelial cells (cHCECs) are anticipated to become an alternative to donor corneas for the treatment of corneal endothelial dysfunction.
Munetoyo Toda +7 more
semanticscholar +1 more source
Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic haematopoietic cells in cancer: From biology to therapy [PDF]
, 2009 Vascularization, a hallmark of tumorigenesis, is classically thought to occur exclusively through angiogenesis (i.e. endothelial sprouting). However, there is a growing body of evidence that endothelial progenitor cells (EPCs) and proangiogenic ...
Bogos, Krisztina +9 more
core +1 more source
Fish Scale-Derived Scaffolds for Culturing Human Corneal Endothelial Cells
Stem Cells International, 2018 Purpose To investigate the biocompatibility of fish scale-derived scaffolds (FSS) with primary human corneal endothelial cells (HCEnCs). Methods HCEnCs were isolated from 30 donor corneas in a donor-matched study and plated in precoated Lab-Tek slides (n
Mohit Parekh +4 more
semanticscholar +1 more source