Results 101 to 110 of about 8,732,052 (351)

Temporal regulation of murine cytomegalovirus transcription and mapping of viral RNA synthesized at immediate early times after infection [PDF]

, 1984
The replication of murine cytomegalovirus strain Smith in murine embryonic fibroblasts was investigated at immediate early, early, and late times after infection.
Ebeling-Keil, Angelika, Keil, Günther M., Koszinowski, Ulrich H.   +2 more
core   +1 more source

Estimation of the worldwide seroprevalence of cytomegalovirus : a systematic review and meta-analysis [PDF]

, 2019
Cytomegalovirus (CMV) infection does not usually produce symptoms when it causes primary infection, reinfection, or reactivation because these three types of infection are all controlled by the normal immune system.
Anderholm, Arvin, Bate, Boeckh, Buerkner, Cannon, Cannon, Deayton, Emery, Gkrania-Klotsas, Griffiths, Griffiths, Guerra, Hyde, Institute of Medicine Committee to Study Priorities for Vaccine Development, Kempen, Kenneson, Kharfan-Dabaja, Lilleri, Marty, Moher, Pass, Pembrey, Plotkin, Revello, Richardson, Rubin, Sabbaj, Simanek, Slyker, Vries, Wimperis   +31 more
core   +2 more sources

Human Monoclonal Antibodies Neutralizing Human Cytomegalovirus

Journal of General Virology, 1987
Hybridomas producing human monoclonal antibodies (MAbs) against human cytomegalovirus (CMV) were generated by fusion of human spleen cells and mouse myeloma cells. Two of the six MAbs obtained neutralized viral infectivity even at concentrations lower than 1 microgram/ml. One MAb required complement for neutralization but the other did not.
Y, Masuho, Y, Matsumoto, T, Sugano, S, Fujinaga, Y, Minamishima   +4 more
openaire   +2 more sources

Degradable Donor‐Acceptor Polymeric Mixed Ionic‐Electronic Conductors for Transient Electronics

Advanced Materials Technologies, EarlyView.
Here, we report degradable donor–acceptor (D–A) polymeric mixed ionic‐electronic conductors for transient electronics. We take a systematic side chain engineering approach to elucidate how molecular‐level modifications of donor–acceptor (D–A) polymer structures can satisfy demands that are often conflicting: degradability, charge carrier transport, and
Angela Lin, Zhichang Liu, Saroj Upreti, Stanley Lo, Nathan Sung Yuan Hsu, Xiaodan Gu, Sihong Wang, Helen Tran   +7 more
wiley   +1 more source

CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]

, 2015
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL, Griffiths, PD, Murray, CD, Watkins, J, Webster, DP   +4 more
core   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

High-resolution human cytomegalovirus transcriptome [PDF]

Proceedings of the National Academy of Sciences, 2011
Deep sequencing was used to bring high resolution to the human cytomegalovirus (HCMV) transcriptome at the stage when infectious virion production is under way, and major findings were confirmed by extensive experimentation using conventional techniques.
Gatherer, Derek, Seirafian, Sepehr, Cunningham, Charles, Holton, Mary, Dargan, Derrick J., Baluchova, Katarina, Hector, Ralph D., Galbraith, Julie, Herzyk, Pawel, Wilkinson, Gavin W. G., Davison, Andrew J.   +10 more
openaire   +2 more sources

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

Advanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng, Lulu Zhang, Yimeng Fan, Sijuan Huang, Qingyu Zhao, Chao Han, Zhihui Hao   +6 more
wiley   +1 more source

Characterization of the murine cytomegalovirus early transcription unit e1 that is induced by immediate-early proteins [PDF]

, 1990
The regulation of murine cytomegalovirus early (E) gene expression was studied in the cell line B25, which is stably transfected with the immediate-early ie1/ie3 gene complex.
Bühler, Bernhard, Keil, Günther M., Koszinowski, Ulrich H., Weiland, Frank   +3 more
core   +1 more source

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark, Gazzard, Brian G, Goodier, Martin R, Gregson, John NS, Kuri-Cervantes, Leticia, Mela, Christopher M   +5 more
core   +1 more source