nf-core/detaxizer: a benchmarking study for decontamination from human sequences. [PDF]
Abstract Privacy is paramount in health data, particularly in human genetics, where information extends beyond individuals to their relatives. Metagenomic datasets contain substantial human genetic material, necessitating careful handling to mitigate data leakage risks when sharing or publishing. The same applies to genetic datasets from
Seidel J, Kaipf C, Straub D, Nahnsen S.
europepmc +8 more sources
Transplantation of Human Fetal Tissue for Neurodegenerative Diseases: Validation of a New Protocol for Microbiological Analysis and Bacterial Decontamination [PDF]
Restorative cell therapy concepts in neurodegenerative diseases are aimed at replacing lost neurons. Despite advances in research on pluripotent stem cells, fetal tissue from routine elective abortions is still regarded as the only safe cell source ...
Tobias Piroth +7 more
doaj +2 more sources
Optimizing mycobacteria molecular diagnostics: No decontamination! Human DNA depletion? Greener storage at 4 °C! [PDF]
IntroductionTuberculosis (TB) is an infectious disease caused by the group of bacterial pathogens Mycobacterium tuberculosis complex (MTBC) and is one of the leading causes of death worldwide.
Prajwal Prajwal +10 more
doaj +2 more sources
Identification of Novel Simulants for Toxic Industrial Chemicals and Chemical Warfare Agents for Human Decontamination Studies: A Systematic Review and Categorisation of Physicochemical Characteristics. [PDF]
James T, Collins S, Marczylo T.
europepmc +3 more sources
Environmental and decontamination issues for human coronaviruses and their potential surrogates [PDF]
AbstractPandemic coronavirus disease‐2019 (COVID‐19) gives ample reason to generally review coronavirus (CoV) containment. For establishing some preliminary views on decontamination and disinfection, surrogate CoVs have commonly been assessed. This review serves to examine the existing science in regard to CoV containment generically and then to ...
Nevio Cimolai
openalex +3 more sources
This study compared the efficiency for in vitro human skin decontamination using DDGel and RSDL. Experiments were performed using in vitro human skin models, in which skin was mounted onto Flow-Through diffusion cells. The mass of 14-C CEES removed from skin surface after decontamination was quantitated by measuring radioactivity with a liquid ...
Yachao Cao +4 more
openalex +4 more sources
Determination of ethyl glucuronide in human hair samples: Decontamination vs extraction [PDF]
AbstractDecontamination of samples prior to analysis is common practice and recommended for ethyl glucuronide (EtG) hair testing. The aim of this study was to evaluate the applied decontamination procedure during routine hair EtG analysis by monitoring the ethyl glucuronide concentrations in the washing solutions from a representative cohort of ...
Alexander Müller +1 more
openalex +3 more sources
Prophylactically Decontaminating Human Islet Product for Safe Clinical Application
Transplanting pancreatic islets into recipients must be safe and effective to treat Type 1 diabetes. Islet quality and quantity are important, however, the final product must also be free from microbial contamination and low endotoxin levels.This study explored a method to eliminate contamination in manufacturing islets for transplantation.
Meirigeng Qi +10 more
openalex +3 more sources
Human microbial ecology: Lactobacilli, probiotics, selective decontamination
Health care-associated infections are closely associated with different medical interventions which interrupt the balance of human microbiota. The occasional predominance of opportunistic pathogens may lead to their translocation into the lymph nodes and bloodstream, causing endogenous (primary or secondary) hospital infections.
Marika Mikelsaar
openalex +4 more sources

