Results 1 to 10 of about 23,199 (156)

nf-core/detaxizer: a benchmarking study for decontamination from human sequences [PDF]

NAR Genomics and Bioinformatics
Abstract Privacy is paramount in health data, particularly in human genetics, where information extends beyond individuals to their relatives. Metagenomic datasets contain substantial human genetic material, necessitating careful handling to mitigate data leakage risks when sharing or publishing. The same applies to genetic datasets from
Jannik Seidel, Camill Kaipf, Daniel Straub, Sven Nahnsen   +3 more
europepmc   +8 more sources

Optimization and evaluation of new decontamination procedures inactivating human prions

Journal of Hospital Infection
Prions are protein-only infectious agents for which no prophylactic or curative treatment exists. There is a need for formulations effective against human prions and robust in-vitro and in-vivo evaluation protocols.To compare infectivity bioassays with those of their protein misfolding cyclic amplification (PMCA) counterparts to propose a robust method
Herzog, Laetitia, Reine, Fabienne, Castille, Johan, Passet, Bruno, Moudjou, Mohammed, Bonnet, Roger, Torres, Juan Maria, Rezaei, Human, Vilotte, Jean-Luc, Béringue, Vincent, Igel, Angélique   +10 more
openaire   +5 more sources

Environmental and decontamination issues for human coronaviruses and their potential surrogates [PDF]

Journal of Medical Virology, 2020
AbstractPandemic coronavirus disease‐2019 (COVID‐19) gives ample reason to generally review coronavirus (CoV) containment. For establishing some preliminary views on decontamination and disinfection, surrogate CoVs have commonly been assessed. This review serves to examine the existing science in regard to CoV containment generically and then to ...
Nevio Cimolai
openaire   +3 more sources

Prophylactically Decontaminating Human Islet Product for Safe Clinical Application

Transplantation Direct, 2016
Transplanting pancreatic islets into recipients must be safe and effective to treat Type 1 diabetes. Islet quality and quantity are important, however, the final product must also be free from microbial contamination and low endotoxin levels.This study explored a method to eliminate contamination in manufacturing islets for transplantation.
Qi, Meirigeng, Omori, Keiko, Mullen, Yoko, McFadden, Brian, Valiente, Luis, Juan, Jemily, Bilbao, Shiela, Tegtmeier, Bernard R., Dafoe, Donald, Kandeel, Fouad, Al-Abdullah, Ismail H.   +10 more
openaire   +3 more sources

Low-dose ciprofloxacin for selective decontamination of the digestive tract in human volunteers [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 1990
The effect on the faecal aerobic and anaerobic flora of ciprofloxacin given in low doses for selective decontamination of the digestive tract was investigated in ten human volunteers. The volunteers received 50, 100 and 200 mg of ciprofloxacin every 12 h for five days at intervals of three and five weeks respectively.
Meijer-Severs, GJ, van Santen, E, de Vries - Hospers, HG   +2 more
openaire   +4 more sources

Identification of Novel Simulants for Toxic Industrial Chemicals and Chemical Warfare Agents for Human Decontamination Studies: A Systematic Review and Categorisation of Physicochemical Characteristics. [PDF]

Int J Environ Res Public Health, 2021
James T, Collins S, Marczylo T.
europepmc   +5 more sources

Decontamination of Intravaginal Probes Infected by Human Papillomavirus (HPV) Using UV-C Decontamination System [PDF]

Journal of Clinical Medicine, 2019
Background: This three-step study evaluated ultraviolet-C (UV-C) efficacy against human papillomavirus (HPV) found on vaginal ultrasound probes. Methods: The first two steps evaluated UV-C disinfection of vaginal ultrasound probes in routine condition.
Maxime Pichon, Karine Lebail-Carval, Geneviève Billaud, Bruno Lina, Pascal Gaucherand, Yahia Mekki   +5 more
openaire   +3 more sources

Determination of ethyl glucuronide in human hair samples: Decontamination vs extraction [PDF]

Drug Testing and Analysis, 2020
AbstractDecontamination of samples prior to analysis is common practice and recommended for ethyl glucuronide (EtG) hair testing. The aim of this study was to evaluate the applied decontamination procedure during routine hair EtG analysis by monitoring the ethyl glucuronide concentrations in the washing solutions from a representative cohort of ...
Alexander Müller, Stefanie Iwersen‐Bergmann   +1 more
openaire   +2 more sources

In vitro human skin permeation and decontamination of 2-chloroethyl ethyl sulfide (CEES) using Dermal Decontamination Gel (DDGel) and Reactive Skin Decontamination Lotion (RSDL)

Toxicology Letters, 2018
This study compared the efficiency for in vitro human skin decontamination using DDGel and RSDL. Experiments were performed using in vitro human skin models, in which skin was mounted onto Flow-Through diffusion cells. The mass of 14-C CEES removed from skin surface after decontamination was quantitated by measuring radioactivity with a liquid ...
Yachao Cao, Xiaoying Hui, Hanjiang Zhu, Akram Elmahdy, Howard Maibach   +4 more
openaire   +3 more sources

Safety assessment of the process EREMA Vacurema Advanced used to recycle post-consumer PET into food contact materials. [PDF]

EFSA J
EFSA Panel on Food Contact Materials (FCM), Lambré C, Crebelli R, da Silva M, Grob K, Milana MR, Pronk M, Rivière G, Ščetar M, Theodoridis G, Van Hoeck E, Waegeneers N, Dudler V, Papaspyrides C, de Fátima Tavares Poças M, Volk K, Lampi E.   +16 more
europepmc   +1 more source