Results 41 to 50 of about 27,268,237 (302)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Early childhood milk and milk products intake - Maternal perceptions & practices

International Journal of Endorsing Health Science Research, 2013
The prevalence of micronutrient deficiencies in young children has a profound effect on their immune system, growth and mental development. However, many micronutrients deficiencies in children such as calcium can be prevented. This research has explored
Asma Shehzad Makhani, Ayesha Zahid Khan, Ghazala Rafique Rafique   +2 more
doaj   +1 more source

Mental health and psychological well-being of Kenyan adolescents from Nairobi and the Coast regions in the context of COVID-19

Child and Adolescent Psychiatry and Mental Health, 2023
Background Despite the high burden of mental health problems during adolescence and its associated negative consequences, it has remained neglected especially in sub-Saharan Africa.
Gideon Mbithi, Adam Mabrouk, Ahmed Sarki, Rachel Odhiambo, Mary Namuguzi, Judith Tumaini Dzombo, Joseph Atukwatse, Margaret Kabue, Paul Mwangi, Amina Abubakar   +9 more
doaj   +1 more source

Role of the microbiome in human development

Gut, 2019
The host-microbiome supraorganism appears to have coevolved and the unperturbed microbial component of the dyad renders host health sustainable. This coevolution has likely shaped evolving phenotypes in all life forms on this predominantly microbial ...
M. Dominguez-Bello, F. Godoy-Vitorino, R. Knight, M. Blaser   +3 more
semanticscholar   +1 more source

Global Indicators of Sustainable Development: Evaluation of the Influence of the Human Development Index on Consumption and Quality of Energy

Energies, 2020
The article explores the impact of the quality and volume of energy consumption of the population on the human development index using a sample of a number of countries as an example.
A. Yumashev, B. Ślusarczyk, S. Kondrashev, A. Mikhaylov   +3 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Caregiving experiences and practices: qualitative formative research towards development of integrated early childhood development interventions targeting Kenyans and refugees in Nairobi’s informal settlements

BMC Public Health
Background Evidence is needed to understand factors that influence child development and caregiving experiences, especially in marginalized contexts, to inform the development and implementation of early childhood development (ECD) interventions.
Vibian Angwenyi, Amina Abubakar, Margaret Kabue, Eunice Njoroge, Carophine Nasambu, Derrick Ssewanyana, Stephen Mulupi, Joyce Marangu, Eunice Ombech, Mercy Moraa Mokaya, Emmanuel Kepha Obulemire, Linlin Zhang, Greg Moran, Kerrie Proulx, Tina Malti, Marie-Claude Martin, Stephen Lye, Kofi Marfo   +17 more
doaj   +1 more source

X chromosome inactivation in human development

Development, 2020
X chromosome inactivation (XCI) is a key developmental process taking place in female mammals to compensate for the imbalance in the dosage of X-chromosomal genes between sexes.
C. Patrat, Jean-François Ouimette, C. Rougeulle   +2 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source