Results 241 to 250 of about 597,824 (308)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Counting Sexes and Gender: Reflections on a Timeless Tension at the Heart of Psychology. [PDF]

Arch Sex Behav
Mazur LB, Mazur T.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Cultural innovation can increase and maintain biodiversity: A case study from medieval Europe. [PDF]

Proc Natl Acad Sci U S A
Spitzig A, Rösch M, Woodbridge J, Bauch M, Guzowski P, Erhart P, Fyfe R, Marinova E, Izdebski A.   +8 more
europepmc   +1 more source

Globalization and Cosmopolitanism: Tracing a Kantian Trajectory to Peace [PDF]

, 2006
Rossi, Philip J.
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Complexity and psychopathology: from mechanistic science to a physical understanding of the mental conditions based on chaos and complexity. [PDF]

Front Psychiatry
Abramov DM.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Turkish Thoracic Society Declaration on Peace and Health the Importance of Breathing in a World Without War. [PDF]

Thorac Res Pract
Çetinkaya PD, Töreyin ZN, Yüce Özdemir H, Yasin Y, Kılınç O, Yorgancıoğlu A, Çalışır HC, Çuhadaroğlu Ç, Köktürk N, Demirdöğen E, Öcal N, Bingöl Z, Gürün Kaya A, Esendağlı D, Yıldız E, Balcan MB, Çil B, Kılıçgün H, Begiç E.   +18 more
europepmc   +1 more source

Diversity as the Fuel of Theory: Demographic Biases in CHILDES and Its Commentaries. [PDF]

Dev Sci
Scaff C, Loukatou G, Cristia A, Havron N.   +3 more
europepmc   +1 more source