Results 251 to 260 of about 5,584,973 (385)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Global and regional trends in under-five diarrheal disease burden: impact of human development index and geographic disparities, 1990-2021. [PDF]

Gastroenterol Hepatol Bed Bench
Azizmohammad Looha M, Saberi Shahrbabaki A, Mohammadpoor A, Zamani M, Sadeghloo Z, Jameie M, Mousavi H, Pooresmaeil Niaki SR, Mohebbi H, Asadimanesh N, Norouzi F, Banar S, Jalalinejad M, Yousefi M, Shahreki Mojahed S, Masheghati F, Ghalandarlaki M, Bahadorimonfared A.   +17 more
europepmc   +1 more source

Association between Suicide Rate and Human Development Index, Income, and the Political System in 46 Muslim-Majority Countries: An Ecological Study. [PDF]

Eur J Investig Health Psychol Educ, 2022
Arafat SMY, Marthoenis M, Khan MM, Rezaeian M.   +3 more
europepmc   +1 more source

Linking Human Development and the Financial Responsibility of Regions: Combined Index Proposals Using Methods From Data Envelopment Analysis

, 2019
Diogo Ferraz, Enzo Mariano, Daisy Rebelatto, Dominik Hartmann   +3 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Disparities in wellbeing in the USA by race and ethnicity, age, sex, and location, 2008-21: an analysis using the Human Development Index. [PDF]

Lancet
Dwyer-Lindgren L, Kendrick P, Baumann MM, Li Z, Schmidt C, Sylte DO, Daoud F, La Motte-Kerr W, Aldridge RW, Bisignano C, Hay SI, Mokdad AH, Murray CJL.   +12 more
europepmc   +1 more source

Relationship between socio-demographic correlates and human development index with physical activity and sedentary time in a cross-sectional multicenter study. [PDF]

BMC Public Health, 2022
Ferrari G, Farías-Valenzuela C, Guzmán-Habinger J, Drenowatz C, Marques A, Kovalskys I, Gómez G, Rigotti A, Cortés LY, Yépez García MC, Pareja RG, Herrera-Cuenca M, Marconcin P, Chávez JL, Fisberg M.   +14 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Human Development and Economic Uncertainties: Exploring Another Dimension of Development

Lahore Journal of Economics
This study makes the case that economic uncertainties—i.e., the extent to which economies face systemic uncertainties—need to be considered another dimension of human development because they render development vulnerable, diminish social welfare, and ...
Jamshed Y. Uppal, Syeda Rabab Mudakkar
doaj  

Correction: Burden of type 2 diabetes and its relationship with human development index in Asian countries: Global Burden of Disease Study in 2019. [PDF]

BMC Public Health
Alinaghian SA, Hamidzadeh S, Badrizadeh A, Khazaei Z, Souri A, Momenabadi V, Goodarzi E.   +6 more
europepmc   +1 more source