Results 51 to 60 of about 1,193,129 (257)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
An Analytical Study on the Impact of Development-Driven Education on Environmental Improvement with Emphasis on the Human Development Index [PDF]
The present study aims to present an analytical review of the relationship between development-driven education and environmental improvement. Previous research in this field has often examined the effect of environmental pollution on the human ...
Ali Shojaeifard, Samira Motaghi
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Human Development Index: suggested corrections
Full substitutability and equal weighting principles of the human development index (HDI) have been found to be ineffective in determining appropriate HDI values and should therefore be dropped.
P. PALAZZI, A. LAURI
doaj
Analisis Kausalitas Pertumbuhan Ekonomi terhadap Indeks Pembangunan Manusia
Human development is one of the indicators of the success of economic growth. The good quality of human resources goes hand in hand with economic growth, this is because resources as part of the factor of production are the most valuable assets in the ...
Muslikhati Muslikhati
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Community Welfare Perspective Islamic Human Development Index (IHDI)
Purpose: This study aims to analyze community welfare through the Islamic Human Development Index (IHDI) framework Design/methodology: Utilizing a Comprehensive Literature Review (CLR) approach, the research examines previous studies indexed in Scopus ...
Ahmad Yunadi +2 more
doaj +1 more source

