Results 81 to 90 of about 3,317,170 (346)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Composite Indices of Human Well-being: Past, Present, and Future [PDF]
human well-being, composite well-being indices, income per capita, Human Development Index, Physical Quality of Life ...
McGillivray, Mark, Noorbakhsh, Farhad
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Designing the Inequality-Adjusted Human Development Index (HDI) [PDF]
This paper proposes a method for adjusting the HDI to reflect the distribution of human development achievements across the population, and across dimensions, using an inequality measure from the Atkinson family.
Sabina Alkire and James Foster
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Revised Human Development Index
, 2017 This paper is a case study of HDI where the ASEAN countries were used as the subject of analysis and the OECD countries were used as a comparison group. We propose to revise the current human development index. HDI employs three components to measure human development, namely life expectancy, education and the standard of living.
openaire +1 more source
Engendering Human Development: A Critique of the UNDP’s Gender-Related Development Index [PDF]
This article reviews the literature critiquing the United Nations Development Programme’s Gender-related Development Index (GDI), which is a measure of human development penalized for the extent of gender inequality in each country; presents several ...
Elizabeth Stanton
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Correlation Between Human Development Index and Economic Growth of Major Oil and Gas Producers
, 2023 Kateřina PEKARČÍKOVÁ +1 more
openalex +2 more sources