Results 141 to 150 of about 831,336 (352)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
An algorithm for the systematic disturbance of optimal rotational solutions [PDF]
An algorithm for introducing a systematic rotational disturbance into an optimal (i.e., single axis) rotational trajectory is described. This disturbance introduces a motion vector orthogonal to the quaternion-defined optimal rotation axis.
Grunwald, Arthur J., Kaiser, Mary K.
core +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Securing the future of Hainan’s Tropical Rainforest: challenges and strategies for conservation
Frontiers in Forests and Global ChangeThe Hainan’s Tropical Rainforest is China’s largest and best-preserved tropical rainforest, holding critical biodiversity value in the Indo-Burma biodiversity hotspot.
Shijie Wang, Chunping Xie
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Disturbances in human arm movement trajectory due to mild cerebellar dysfunction. [PDF]
, 1990 S.H. Brown +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Hypohydration and Mood State in Free-Living Males and Females [PDF]
, 2015 Previous research has shown that acute dehydration can result in changes in mood. These changes have been reported in less than a 1% loss in total body water. However, the effect of hypohydration (i.e., reflected through high urine concentration) on mood
Vidal, Thomas Edward
core +2 more sources
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Environmental Impacts of Mountain Biking: Science Review and Best Practices [PDF]
, 2007 Mountain biking is still a relatively new activity whose environmental impact and contribution to trail degradation is poorly understood. As with all recreational pursuits, it is clear that mountain biking contributes some degree of environmental ...
Jeff Marion, Jeremy Wimpey
core