Results 81 to 90 of about 224,924 (249)

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

open access: yesAdvanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz   +10 more
wiley   +1 more source

The holistic concepts of disaster management and social cohesion - statistics and method [PDF]

open access: yesBuletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2011
The paper uses a multidisciplinary approach to underline the importance of some holistic concepts like social cohesion and human ecology, and also to assess environmental and economic specificity of these new ecological and social terms. The structure of
Gheorghe SĂVOIU
doaj  

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Human ecology

open access: yes, 2015
Me han indicado que mi tópico de hoy es la ecología humana. Primero veremos qué quieren decir esas dos palabras; ecología humana es la ciencia que estudia el volumen y la distribución territorial y la organización de las comunidades en relación con el medio en que viven, dedicando especial atención a los procesos de competencia y cooperación que en ...
openaire   +3 more sources

Health, biodiversity, and natural resource use on the Amazon frontier: an ecosystem approach

open access: yesCadernos de Saúde Pública
This study aims to improve the health of rural Amazonian communities through the development and application of a participatory ecosystem approach to human health assessment. In the study area marked seasonal fluctuations dictate food availability, water
Tamsyn P. Murray, José Sánchez-Choy
doaj  

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

open access: yesAdvanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil   +7 more
wiley   +1 more source

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

open access: yesAdvanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su   +13 more
wiley   +1 more source

In search of human ecology: memories, insights, and wider points of view (a personal journey)

open access: yesForum Sociológico
This article is a narrative memoir of the author’s personal engagement with the intellectual and institutional history of human ecology. Written in essay style, it explores a blend of themes and approaches based on a lifetime of interdisciplinary inquiry.
Richard J. Borden
doaj   +1 more source

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