Results 111 to 120 of about 4,206,748 (294)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Automatic Speech Recognition in Air Traffic Control: a Human Factors Perspective [PDF]

open access: yes, 1990
The introduction of Automatic Speech Recognition (ASR) technology into the Air Traffic Control (ATC) system has the potential to improve overall safety and efficiency.
Karlsson, Joakim
core   +1 more source

Identification and Evaluation of Human Errors Using Human Factor Analysis and Classification System based on Fuzzy Hierarchy Theory: A Case Study in the Cement Industry

open access: yesطب کار, 2019
Introduction: Human factors studies have shown that about 80% of the root causes of major accidents affecting safety, the environment or ergonomics are related to human error.
davod afshari   +3 more
doaj  

Comparison of Two Human Error Evaluation Techniques (HET and SHERPA) in Gas Supply Operations using AHP

open access: yesبهداشت و ایمنی کار, 2020
Introduction: The development of residential and industrial areas has led to increasing gas consumption and overcrowding in gas supply networks. Accordingly, hazards and risks caused by human errors, processing and mechanical failures in pipelines, and ...
Gholam Abbas Shirali   +2 more
doaj  

Using artificial intelligence to avoid human error in identifying embryos: a retrospective cohort study. [PDF]

open access: yesJ Assist Reprod Genet, 2022
Hammer KC   +8 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Impact of Fireworks Industry Safety Measures and Prevention Management System on Human Error Mitigation Using a Machine Learning Approach. [PDF]

open access: yesSensors (Basel), 2023
Nallathambi I   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

the Identify, evaluate and control the errors of the treatment staff in the laboratory unit and provide corrective measures using barrier analysis

open access: yesInternational Journal of Occupational Hygiene, 2020
Introduction: Laboratory unit is one of the most dangerous working environments in which the occurrence of errors can lead to severe injuries to patients, psychological damages to the service providers, degradation of the unit and legal consequences.In ...
Gazal Mahroozadeh   +2 more
doaj  

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