Results 51 to 60 of about 7,670,718 (301)

Hybrid Uracil Derivatives with Caffeine and Gramine Obtained via Click Chemistry as Potential Antioxidants and Inhibitors of Plant Pathogens

open access: yesMolecules
A series of novel hybrid uracil derivatives incorporating the natural alkaloids caffeine or gramine, linked via 1,2,3-triazole ring, were synthetized using click chemistry. The structures of the obtained compounds were confirmed by spectroscopic methods,
Milda Szlaużys   +6 more
doaj   +1 more source

Two functional reticulocyte binding-like (RBL) invasion ligands of zoonotic Plasmodium knowlesi exhibit differential adhesion to monkey and human erythrocytes

open access: yesMalaria Journal, 2012
Background Plasmodium knowlesi is a monkey malaria species that is becoming a serious public health concern infecting hundreds and perhaps thousands of humans in Southeast Asia.
Semenya Amma A   +4 more
doaj   +1 more source

Hypoxanthine uptake by human erythrocytes [PDF]

open access: yesFEBS Letters, 1979
It is well established that the uptake of hypoxan- thin, by human erythrocytes is mediated by its incorporation into IMP [ 11. The synthesis of this nucleotide is dependent on the intracellular availability of 5phosphoribosyl o-1-pyrophosphate (PRPP) and on the activity of hypoxanthine-guanine phospho- ribosyltransferase (HGPRT) [ 11.
GIACOMELLO, Alessandro   +1 more
openaire   +3 more sources

Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies [PDF]

open access: yes, 2012
Contains fulltext : 109602.pdf (Publisher’s version ) (Open Access)Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous ...
Dinkla, S.   +19 more
core   +3 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Pneumococcal immune adherence to human erythrocytes

open access: yes, 2003
Background Human red blood cells bind various C3b-coated microorganisms via their C3b/CR1 receptor, a phenomenon referred to as immune adherence.
Kimpen, JLL   +17 more
core   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Large‐Scale Ex Vivo Generation of Human Red Blood Cells from Cord Blood CD34+ Cells

open access: yesStem Cells Translational Medicine, 2017
The ex vivo generation of human red blood cells on a large scale from hematopoietic stem and progenitor cells has been considered as a potential method to overcome blood supply shortages.
Yu Zhang   +10 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

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