Results 51 to 60 of about 100,513 (261)
Karl Marx on species essence of a human being
The article is based on a detailed textual analysis is the attempt of historicalphilosophical explication of the formation of Karl Marx’s teaching about the species essence of human beings (Gattungswesen des Menschen).
Pyotr N. Kondrashov
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REGIONAL HUMAN CAPITAL: PROBLEMS OF ESSENCE, STRUCTURE AND ASSESSMENT
This article considers main questions appear in comtemporary circumstances while studying human capital on regional level: problems of understanding and aggregation, human capital structuring and assessment.
Olga V. Zabelina +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Voluntarisme (Filsafat Kehendak) dalam Filsafat Barat
In the long history of Western Philosophy, philosophical thoughts were dominated by rationalist clan. This rationalist clan posed the mind (to think) as the essence of human-being (Cogito Ergo Sum).
Misnal Munir
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Law and Literature.The Places for Metaphysical Thinking.
Objectives The aim of this study is to identify places of metaphysical thinking in law and in literature.As metaphysical thinking is the search for the causes of reality which, as principia (arché), are its material and the development principle.
Dorota Anna Łażewska
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Philosophical Approaches to Religion in the Perspective of the Concept of "Human Essence"
In the paper we have attempted to reconstruct and summarize the main theses and approaches regarding the concept of religion, as formed by some known philosophers and theologians, thinkers who took "Man", the "human essence", "human nature" as the ...
Nonka Bogomilova
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