Results 221 to 230 of about 3,138,101 (337)

Focal Coordination and Language in Human Evolution. [PDF]

Hum Nat
Myerson R.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Role playing in human evolution: from life to art, and everything in between. [PDF]

Front Psychol
Brown S.
europepmc   +1 more source

Molecular Evolution of Human Influenza A/H3N2 Virus in Asia and Europe from 2001 to 2003

, 2005
X. Sherry, Trentice V. Bolar, Ping Zhao, John S. Tam, Ruth Rappaport, Sheau‐Mei Cheng   +5 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

How Patient, Infection, and Cyst Characteristics Impact the Evolution of Taenia Solium Larva in the Human Brain: A Unique Cyst-Level Analysis

Hongbin Zhang, Meghana G. Shamsunder, Pryanka Bawa, Arturo Carpio, W. Allen Hauser, Karina Quinde-Herrera, Alex Jaramillo, Elizabeth A. Kelvin   +7 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Massively parallel approaches for characterizing noncoding functional variation in human evolution. [PDF]

Curr Opin Genet Dev
Rong S, Root E, Reilly SK.
europepmc   +1 more source

Bodily mimesisas “the missing link” in human cognitive evolution

, 2005
Jordan Zlatev, Tomas Persson, Peter Gärdenfors   +2 more
openalex   +1 more source

Body Growth and Life History of Modern Humans and Neanderthals from the Perspective of Human Evolution

, 2016
Taro Yamauchi
openalex   +1 more source