Results 131 to 140 of about 8,394,024 (298)
Application of "Human Factor Analysis and Classification System" (HFACS) Model to the Prevention of Medical Errors and Adverse Events: A Systematic Review. [PDF]
Int J Prev Med, 2023 Jalali M +3 more
europepmc +1 more source
INTELLECTUAL CAPITAL COMPONENTS AS CAUSES OF REGIONAL DISPARITIES. A CASE STUDY IN ROMANIA [PDF]
Starting from a Logit model developed in the past we try to provide empirical support for counties disparities regarding intellectual capital factor influence. The study presents some correlation between economic performance, structure of activity in the
Alexandru Isaic-Maniu +2 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Fatigue as a key human factor in complex sociotechnical systems: Vessel Traffic Services. [PDF]
Front Public Health, 2023 Crestelo Moreno F +8 more
europepmc +1 more source
A Versus K Revisited: Evidence from Selected MENA Countries [PDF]
This paper reconsiders the A versus K debate, namely, which factor is the leading contributor to economic growth? productivity gains (A) or factor accumulation (K).
Aamer Abu-Qarn, Suleiman Abu-Bader
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Механика машин, механизмов и материалов, 2019 A method of monitoring perception of semantically binary relevant information by a driver in highly automated vehicles is presented for the first time, taking into account information flows circulating in the vehicle’s on-board systems, the driver’s ...
Vladimir V. Savchenko
doaj
Ethacrynic acid is an inhibitor of human factor XIIIa. [PDF]
BMC Pharmacol Toxicol, 2022 Kar S, Vu K, Mottamal M, Al-Horani RA.
europepmc +1 more source