Results 241 to 250 of about 8,394,024 (298)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
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2021
Human factors are integral to applied academic programs such as interaction design. In this chapter, the authors begin by reviewing precepts of authentic, “real-world” learning. From a human factors and interaction design viewpoint, they then describe an authentic learning project—a mobile application design—that was done by university students in ...
Emily Cooney +4 more
+4 more sources
Human factors are integral to applied academic programs such as interaction design. In this chapter, the authors begin by reviewing precepts of authentic, “real-world” learning. From a human factors and interaction design viewpoint, they then describe an authentic learning project—a mobile application design—that was done by university students in ...
Emily Cooney +4 more
+4 more sources
Journal of Psychiatric and Mental Health Nursing, 1996
Defining the core activity of psychiatric nursing is helpful if the discipline seeks profession‐alization. A definition offers a sense of stability within the current culture of change in care provision. However, core activity may be incongruent with postmodern ideas and practice. The Paper attempts to square this circle. It addresses the complexity of
B, Hill, S, Michael
openaire +2 more sources
Defining the core activity of psychiatric nursing is helpful if the discipline seeks profession‐alization. A definition offers a sense of stability within the current culture of change in care provision. However, core activity may be incongruent with postmodern ideas and practice. The Paper attempts to square this circle. It addresses the complexity of
B, Hill, S, Michael
openaire +2 more sources
IEEE Software, 2017
This installment reports on five papers from the 39th International Conference on Software Engineering and its collocated events. These papers focus on human factors in software engineering, with the last three dealing with open source software.
Carver, J. +3 more
openaire +2 more sources
This installment reports on five papers from the 39th International Conference on Software Engineering and its collocated events. These papers focus on human factors in software engineering, with the last three dealing with open source software.
Carver, J. +3 more
openaire +2 more sources
Practical Radiation Oncology, 2016
As I near the end of my medical career, which I began as a family physician and am now ending as a radiation oncologist, there has been one constant throughout this time span and varied career: the central importance and therapeutic value of the patient-doctor relationship.
openaire +2 more sources
As I near the end of my medical career, which I began as a family physician and am now ending as a radiation oncologist, there has been one constant throughout this time span and varied career: the central importance and therapeutic value of the patient-doctor relationship.
openaire +2 more sources