Results 81 to 90 of about 8,394,024 (298)
Transport, 2012 The human factor is one of the most dominant causes of railway accidents. For example, human impact appears to be the main reason for 44% of railway accidents in the Republic of Serbia. Thus, a remarkable effort is undertaken to investigate human factors.
Milan Marković +2 more
doaj +1 more source
Human refuse as a major ecological factor in medieval urban vertebrate communities [PDF]
, 2000 Organic refuse, such as food and butchery waste, was commonly deposited in dumps andpits in medieval towns throughout northern Europe. These deposits of refuse attracted and supponed a diverse communily of scavengers and their predators.
O'Connor, T.P.
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function [PDF]
, 2014 Xanthine oxidase (XOD) is an enzyme which plays a central role in purine catabolism by converting hypoxanthine into xanthine and then further into uric acid.
Abooali, Maryam +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Scientific ReportsTo optimize screen quality for a better and healthier visual experience, it is essential to understand how photometric parameters impact ocular physiological parameters. However, the relationship between these photometric and physiological parameters has
Jianqi Cai +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Journal of Environmental Engineering and Landscape Management, 2015 The connection has been found between the course of cardiovascular diseases (CVD) and the hard cosmic ray flux (HCRF) near the ground surface in Vilnius. The course of air temperature and number of sunspot was simultaneously considered. The investigation
Dmitrijus Styro, Ana Usovaite
doaj +1 more source
Annotating Object Instances with a Polygon-RNN
, 2017 We propose an approach for semi-automatic annotation of object instances. While most current methods treat object segmentation as a pixel-labeling problem, we here cast it as a polygon prediction task, mimicking how most current datasets have been ...
Castrejon, Lluis +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source