Results 111 to 120 of about 1,734,834 (239)

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. [PDF]

, 2017
PurposeThe RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages ...
Duncan, Todd, Jaworski, Cynthia, Kutty, R Krishnan, Lakkaraju, Aparna, Poliakov, Eugenia, Postnikova, Olga A, Redmond, T Michael, Samuel, William, Tan, Li Xuan   +8 more
core   +2 more sources

Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy. [PDF]

, 2017
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease ...
A Cevik, A Correa-Villasenor, A deAlmeida, A Granger, A Kulkarni, AP Vlahos, C Scholz, Carlin S Long, CL Antos, D Sedmera, DD Lemon, DJ Cao, Douglas D Lemon, J Lu, JP Cardinale, JW Newburger, JW Rossano, JW Rossano, Karin Nunley, Katharina M Lutter, KB Schuetze, Kimberly M Demos-Davies, KM Demos-Davies, M Tanno, MA Cavasin, MA Cavasin, Maria A Cavasin, MP Gupta, OA O'Connor, PA Marks, PC Frommelt, Q Yang, R Kirk, RG Ohye, S Chen, Sam Payne, SD Miyamoto, SD Miyamoto, SD Miyamoto, Shelley D Miyamoto, SJ Nakano, SK Mani, SM Williams, TA McKinsey, TG Gillette, Timothy A McKinsey, VM Klimek, Weston W Blakeslee, WJ Kowalski, WW Blakeslee   +49 more
core   +1 more source

A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]

, 2013
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo, BIONDI ZOCCAI, GIUSEPPE, CALOGERO, ANTONELLA, CAVARRETTA, Elena, CHIMENTI, ISOTTA, DE FALCO, ELENA, Fabrizio D'Ascenzo, FRATI, GIACOMO, Luca Pacini, MANCONE, Massimo, Maria Emiliana Caristo, MARULLO, Antonino, Marzia Lotrionte, Omar Leoni, PERUZZI, MARIANGELA, PETROZZA, Vincenzo   +15 more
core   +3 more sources

Late systolic central hypertension as a predictor of incident heart failure : the Multi-Ethnic Study of Atherosclerosis [PDF]

, 2015
Background: Experimental studies demonstrate that high aortic pressure in late systole relative to early systole causes greater myocardial remodeling and dysfunction, for any given absolute peak systolic pressure.
Bluemke, David A, Brumback, Lyndia, Chirinos Medina, Julio, Duprez, Daniel A, Jacobs, David R, Kronmal, Richard, Ouyang, Pamela, Segers, Patrick, Townsend, Raymond R, Vaidya, Dhananjay, Zamani, Payman   +10 more
core   +1 more source

Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2) [PDF]

, 2017
Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of con-firmed HF cases in the United States. However, there are no highly effective evidence-basedtreatments currently available for these patients.
Abbate, Antonio, Abouzaki, Nayef, Arena, Ross, Biondi-zoccai, Giuseppe, Buckley, Leo F., Canada, Justin M., Carbone, Salvatore, Dixon, Dave L., Oddi-erdle, Claudia, Trankle, Cory R., Van Tassell, Benjamin W.   +10 more
core   +1 more source

Leveraging Ergonomics and Human Factors (E/HF) for community impact: what have we learned about how to make a difference

Ergonomics
Ergonomics and Human Factors (E/HF) practitioners are increasingly engaged in projects meant to centre underserved communities and reduce inequities. The subdiscipline of E/HF that has emerged to explore the application of E/HF in this way is called community ergonomics.
Hanna J. Barton, Maurita T. Harris, Courtney C. Rogers, Karen Lange-Morales, Andrew Thatcher, Leah C. Newman, Abigail R. Wooldridge, Wendy A. Rogers, Enid Montague, Nicole E. Werner, Rupa S. Valdez   +10 more
openaire   +2 more sources

CD133 defines hair-inductive cells in the dermal papilla

Scientific Reports
A major contributing factor to the failure of cell-based human hair follicle (HF) engineering is our inability to cultivate highly specialized, inductive mesenchymal fibroblasts, which reside in a unique niche at the HF base, called the dermal papilla ...
Huangying Zhao, Linli Zhou, Lindsey G. Siegfried, Steven Boyce, Dorothy Supp, Thomas Andl, Yuhang Zhang   +6 more
doaj   +1 more source

Factors of Human Resources Competitiveness in Maritime Transport [PDF]

TransNav, 2012
Studying competitiveness of human resources in maritime transport is a complex issue as it depends on several factors like organizational structure of shipping companies, social climate on board ship, multinational work environment, organizational ...
Eugen Barsan, Felicia Surugiu, Cristina Dragomir   +2 more
doaj  

What is Human Factors Compared to Crew Resource Management? [PDF]

TransNav, 2007
The expression Human Factors can be interpreted in two different ways. Firstly: Human Factors is theoretical knowledge based on psychology and CRM is the practical use of that knowledge. Secondly: Human Factors is a concept, which we all too often hear
Gunnar Fahlgren
doaj  

Proteomic Associations of Adverse Outcomes in Human Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Identifying novel molecular drivers of disease progression in heart failure (HF) is a high‐priority goal that may provide new therapeutic targets to improve patient outcomes.
Marie‐Joe Dib, Michael G. Levin, Lei Zhao, Ahmed Diab, Zhaoqing Wang, Christina Ebert, Oday Salman, Joe David Azzo, Sushrima Gan, Payman Zamani, Jordana B. Cohen, Dipender Gill, Stephen Burgess, Loukas Zagkos, Vanessa van Empel, A. Mark Richards, Rob Doughty, Ernst R. Rietzschel, Karl Kammerhoff, Erika Kvikstad, Joseph Maranville, Peter Schafer, Dietmar A. Seiffert, Francisco Ramirez‐Valle, David A. Gordon, Ching‐Pin Chang, Ali Javaheri, Douglas L. Mann, Thomas P. Cappola, Julio A. Chirinos   +29 more
doaj   +1 more source