Results 191 to 200 of about 1,962,192 (329)

Minimal repeats are ubiquitous sites of crossover and recombination across the human genome. [PDF]

BMC Genomics
Ohadi M, Tajeddin N, Bayat H, Annear DJ, Maddi AMA, Khorshid HRK, Kavousi K, Delbari A, Nikkhah A, Arabfard M.   +9 more
europepmc   +1 more source

Structure and Expression of an Integrated Human Papillomavirus Type 16 Genome Amplified in a Cervical Carcinoma Cell Line

, 1989
Hiroshi Shirasawa, Y Tomita, Akira Fuse, Takahiko Yamamoto, H Tanzawa, S Sekiya, H Takamizawa, B. Simizu   +7 more
openalex   +1 more source

Comprehensive, human cellular protein databases and their implication for the study of genome organization and function [PDF]

, 1989
Julio E. Celis, Gitte P. Ratz, Peder Madsen, Borbala Gesser, Jette B. Lauridsen, Sianette Kwee, Hanne H. Rasmussen, Henrik Nielsen, Dorthe Gylling Crüger, Bodil Basse, Henrik Leffers, Bent Honoré, Olaf Møller, Ariana Celis, Joël Vandekerckhove, Guy Bauw, Jo Van Damme, Magda Puype, Marc Van den Bulcke   +18 more
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

NIH gearing up to tackle the human genome [PDF]

, 1988
Joseph Palca
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Anticipatory gaps challenge the public governance of heritable human genome editing. [PDF]

J Med Ethics
Rueda J, Segers S, Hopster J, Kudlek K, Liedo B, Marchiori S, Danaher J.   +6 more
europepmc   +1 more source

Ethical consequences of full human genome testing [PDF]

, 2017
Lupton, Michael
core   +2 more sources

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

The human genome encodes a multitude of novel miRNAs. [PDF]

Nucleic Acids Res
Gao F, Wang F, Chen Y, Deng B, Yang F, Cao H, Chen J, Chen H, Qi F, Kapranov P.   +9 more
europepmc   +1 more source