Results 61 to 70 of about 11,305,394 (400)
Journal of Genetic Engineering and BiotechnologyIntroduction: The fluorescence in situ hybridization (FISH) is a very important technique, as it can diagnose many genetic disorders and cancers. Molecular cytogenetic analysis (FISH) can diagnose numerical chromosome aberrations, sex chromosomes ...
Amal M. Mohamed +7 more
doaj +1 more source
Egyptian Journal of Medical Human Genetics, 2020 Background Short stature is defined as a body height below the third percentile, based on chronological age, or 2 standard deviations (SD) below the national height standard. The prevalence of short stature is around 2% of children worldwide.
Ola M. Eid +9 more
doaj +1 more source
Unconventional machine learning of genome-wide human cancer data
, 2020 Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide perspective ...
Bajaj, Sweta R. +7 more
core +1 more source
REAPR: a universal tool for genome assembly evaluation. [PDF]
, 2013 Methods to reliably assess the accuracy of genome sequence data are lacking. Currently completeness is only described qualitatively and mis-assemblies are overlooked.
Berriman, Matthew +5 more
core +2 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Pre-sequencing assessment of RNA-Seq library quality using real-time qPCR
BioTechniquesRNA sequencing (RNA-Seq) is an essential assay for studying transcriptome profiling. Ribosomal RNA (rRNA) comprises more than 80–90% of total cellular RNA; efficient removal is essential for accurately capturing transcriptomes, particularly to sequence ...
Kavya Kottapalli +13 more
doaj +1 more source
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel +6 more
core +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo. [PDF]
, 2014 Staphylococcus aureus is a commensal and major pathogen of humans and animals. Comparative genomics of S. aureus populations suggests that colonization of different host species is associated with carriage of mobile genetic elements (MGE), particularly ...
Gould, KA +5 more
core +2 more sources
National Human Genome Research Institute
Definitions, 2020 The 2011 National Human Genome Research Institute (NHGRI) strategic planCharting a course for genomic medicine from base pairs to bedside (Nature 470: 204 – 213; http://www.genome.gov/27543215) – articulates a vision for genomics research and describes ...
In April, M. Eric D. Green
semanticscholar +1 more source