Results 261 to 270 of about 988,007 (335)

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

A systematic analysis of contemporary whole exome sequencing capture kits to optimise high-coverage capture of CCDS regions. [PDF]

NAR Genom Bioinform
López FV, Ashton JJ, Cheng G, Ennis S.
europepmc   +1 more source

The Human Genome Project and Eugenics

The Linacre Quarterly, 1998
openaire   +4 more sources

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source

Improved circulating tumor DNA identification for detection of esophageal squamous cell carcinoma by enzymatic methyl sequencing and hybrid neural network. [PDF]

Sci Rep
Shen J, Ren Y, Mao Z, Hu Q, Wan Y, Du J, Lai Y, Shao S, Zhang L, Wu H, Li J, Ju S, Tong X, Zhao J, Cao L, Xiong D, Xu C, Xu JC, Jiang D.   +18 more
europepmc   +1 more source

Development and Validation of Amplicon-Based Protocol for Sequencing of Respiratory Syncytial Virus Genome. [PDF]

J Med Virol
Ferrari G, Romano G, Pitrolo AMG, Baldanti F, Piralla A.   +4 more
europepmc   +1 more source

Evaluation of sequencing reads at scale using rdeval. [PDF]

Bioinformatics
Formenti G, Koo B, Sollitto M, Balacco J, Brajuka N, Burhans R, Duarte E, Giani AM, McCaffrey K, Medico JA, Myers EW, Smeds P, Nekrutenko A, Jarvis ED.   +13 more
europepmc   +1 more source

Complete genome sequence of <i>Eubacterium brachy</i> GTC20104 isolated from a human pleural effusion. [PDF]

Microbiol Resour Announc
Yonetamari J, Hayashi M, Muto Y, Tanaka K.   +3 more
europepmc   +1 more source

PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences. [PDF]

Bioinformatics
Pospelova M, Safonova Y.
europepmc   +1 more source

Large-scale genome sequencing reveals population separation and selection signatures in major canyon yaks. [PDF]

BMC Genomics
Li Z, Zhao J, Guo X, Wu S, Wang S, Zhong J, Kangzhu Y, Wang J, Lan D, Wang J.   +9 more
europepmc   +1 more source