Results 261 to 270 of about 662,117 (305)

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

open access: yesAdvanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao   +13 more
wiley   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

open access: yesAdvanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao   +11 more
wiley   +1 more source

Landscape of rare-allele variants in cultivated and wild soybean genomes. [PDF]

open access: yesPlant Genome
Liu Z   +9 more
europepmc   +1 more source

A near telomere-to-telomere phased reference assembly for the male mountain gorilla. [PDF]

open access: yesSci Data
Nelson DR   +13 more
europepmc   +1 more source

Sequencing the gaps: dark genomic regions persist in CHM13 despite long-read advances

open access: yes
Wadsworth ME   +5 more
europepmc   +1 more source

HiBC: a publicly available collection of bacterial strains isolated from the human gut. [PDF]

open access: yesNat Commun
Hitch TCA   +43 more
europepmc   +1 more source

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