Results 31 to 40 of about 133,957 (255)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Deep Integration of Physical and Human Geography: The Pivot of Geography Innovation
Redai diliIn the present state of geography, this study proposes a deep integration of physical and human geography. It involves the integration of knowledge from these two sub-disciplines of geography.
Zhu Hejian
doaj +1 more source
Groundings, 2011 Science is adequate in describing the phenomena that we experience on a daily basis, however it fails to adequately capture or even understand the human agent in all its perceptions, illogicality, emotions and feelings.
Jonathan Bradley
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"Investors are good, if they follow the rules" – power relations and local perceptions in the case of two European forestry companies in Tanzania [PDF]
Geographica Helvetica, 2014 The rapidly increasing interest of foreign investors in land in the global South, also termed land grabbing, has been widely discussed as potentially supportive, but often rather harmful for local populations. Combining a critical livelihoods perspective
M. Locher, U. Müller-Böker
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Geographies of Energy: Key Issues and Challenges towards Spatial Justice Concepts
Energies, 2023 The contemporary world is uneven not only in terms of the quality of life and economic development, but also in cultural issues that define awareness of global development processes.
Marcin Wójcik, Pamela Jeziorska-Biel
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Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
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iScienceSummary: This perspective explores the multifaceted development challenges related to road network expansion in sub-Saharan Africa, where recent infrastructure investments reflect transformative ambitions but also imply socio-ecological tradeoffs.
Lisa Biber-Freudenberger +17 more
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