This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
Human Geography and the hinterland: The case of Torsten Hägerstrand’s ‘belated’ recognition
Seeing Human Geography as a nexus of temporally oscillating concepts, this paper investigates the dissemination of scientific ideas with a focus on extra-scientific factors.
Brauer René, Dymitrow Mirek
doaj +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Analysis of effective factors on integrated local management in peripheral rural settlements of Tehran metropolitan [PDF]
In recent decades, the growth and development process of cities, especially megacities, has gained a very high speed. This issue has been accompanied by a significant increase in population and activity in these cities.
Masoumeh Ghorbani +3 more
doaj
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source
Population, mobility and urban dynamics through everyday socio-spatial practices in the metropolitan public space / Población, movilidad y dinámicas urbanas a través de las prácticas socio-espaciales cotidianas en el espacio público metropolitano [PDF]
In Europe and Latin America the common challenges of urban labyrinth require not postpone its discussion, the pressing problems facing from Impulse from quantitative and qualitative research approaches and creative approaches to overcome the complex and ...
Diego Sánchez-González
doaj
The Human Geography of Human Geography
Dorling, D, Clarke, G
openaire +3 more sources
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Human and Physical Geography: Can We Learn Something from the History of Their Relations?
A short overview of the history of academic geography since the 19th century shows that there has never been a unity of physical and human geography in the past, at least in the form that is strived for today to justify the relevance of geography in ...
Kesteloot Christian +3 more
doaj +1 more source

