Results 241 to 250 of about 4,102,561 (300)

The Urgency of Free Health Service Policy in Increasing Indonesia's Human Development Index

Aceng Ali Awaludin, Restu Widyo Sasongko, Pande Ayu Naya Kasih Permatananda, Heppi Syofya, Untung Gunawan   +4 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Mushroom marvels: understanding their role in human health. [PDF]

Front Nutr
Noreen S, Sultan H, Hashmi B, Aja PM, Atoki AV.   +4 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Protein aggregates and biomolecular condensates: implications for human health and disease. [PDF]

Front Mol Biosci
Navalkar A, Arunagiri A, Kee T, Panchal K, Dick K.   +4 more
europepmc   +1 more source

Promoting Human Health and the Functioning of the Internal Market: The Reaffirmation of the Tobacco Products Directive's Key Objectives in <i>Poland v Parliament and Council, Pillbox 38 and Philip Morris Brands and Others</i>

Samvel Varvaštian
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Potential Benefits of Behaviors and Lifestyle for Human Health and Well-Being. [PDF]

Nutrients
Stachera Ł, Góras K, Janowska K, Muszkat-Pośpiech E, Wojciechowska A, Świderska-Kołacz G, Zmorzyński S, Czerwik-Marcinkowska J.   +7 more
europepmc   +1 more source

Anomaly of Household Cleaning Agents and their Impacts on Human Health and Environment

Md Shafiqul Islam, Susmita Labanya
openalex   +2 more sources