Results 41 to 50 of about 22,629,443 (235)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Participatory Design of Urban Green Spaces to Improve Residents’ Health

open access: yesLand
Urban green space (UGS) has important impacts on human health, but an integrated participatory approach to UGS design for improved residents’ health has been lacking to date.
Bram Oosterbroek   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

UNC Wilmington College of Health and Human Services 2022 impact report

open access: yes, 2022
UNCW College of Health and Human Services' priorities, mission and values, strategic plan, degree progams, and ...
University of North Carolina, Wilmington. College of Health and Human Services
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

College of Health & Human Services professional schools

open access: yes, 2020
Within the College of Health and Human Services (CHHS), three professional schools integrate teaching, community outreach, and research--the School of Health and Applied Human Sciences, the School of Nursing, and the School of Social ...
University of North Carolina, Wilmington. College of Health and Human Services
core   +2 more sources

UNC Wilmington College of Health and Human Services 2023 impact report

open access: yes, 2023
UNCW College of Health and Human Services' priorities, mission and values, strategic plan, degree progams, and ...
University of North Carolina, Wilmington. College of Health and Human Services
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Global premature mortality due to anthropogenic outdoor air pollution and the contribution of past climate change

open access: yesEnvironmental Research Letters, 2013
Increased concentrations of ozone and fine particulate matter (PM _2.5 ) since preindustrial times reflect increased emissions, but also contributions of past climate change. Here we use modeled concentrations from an ensemble of chemistry–climate models
Raquel A Silva   +29 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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