An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman +13 more
core +1 more source
Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities, without obvious tumor masses.
Sonay Güven Karataş +6 more
doaj +1 more source
Kaposi's sarcoma associated with advanced HIV infection: A case report
Acquired immunodeficiency syndrome was recognized in the early 1980s. It was more common in men who had sex with previously healthy men and young people and were affected by atypical pneumopathy caused by an opportunistic microorganism, identified as ...
Rakashree Chakraborty +3 more
doaj +1 more source
Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study [PDF]
In the present study we have performed both a meta-analysis and an analytical study exploring the presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii antibodies in a sample of 143 schizophrenic ...
Luna Del Castillo, Juan De Dios +13 more
core +1 more source
A rare cause of retroperitoneal mass: Castleman's disease
Castleman's disease is a rare lymphoproliferative disorder. It is a pathological diagnosis and rarely diagnosed before surgery. Presentation of disease may be unicentric or multicentric.
Satyaprakash Jindal +6 more
doaj +1 more source
Molecular detection and genotyping of human herpes virus 8 in blood donors in Congo
Objectives. Human herpesvirus 8 (HHV8) is rarely studied in Congo, despite its prevalence in Africa. Among healthy individuals, HHV-8 does not always lead to a life-threatening infection; however, in immunocompromised individuals, it could lead to more severe disease.
Patrina Joseph Iloukou +6 more
openaire +3 more sources
A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence [PDF]
Intrinsic antiviral resistance represents the first line of intracellular defence against virus infection. During herpes simplex virus type-1 (HSV-1) infection this response can lead to the repression of viral gene expression but is counteracted by the ...
Delphine Cuchet-Lourenço +21 more
core +1 more source
ABSTRACT The recent upsurge of cases caused by the newly identified Clade Ib monkeypox virus (MPXV) in the Democratic Republic of the Congo and other countries has emerged as a significant public health concern. A 34‐year‐old male tourist from Venezuela presented in Vienna, Austria, during his travels through Europe with fever, pharyngitis and an ...
Amélie Hampel +10 more
wiley +1 more source

