Results 221 to 230 of about 224,366 (294)

Congenital CMV Infection: Determination of Transplacental Passage of Aciclovir by Ex Vivo Placental Perfusion

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 6, Page 1241-1248, May 2026.
ABSTRACT Objective To quantify the transplacental transfer of aciclovir at an amount equivalent to 2 g of valaciclovir corresponding to the fractionated dosing regimen given four times daily used to reduce congenital cytomegalovirus (CMV) transmission and to treat the CMV‐infected fetus. Design Experimental ex vivo study.
Helyett Ollivier   +9 more
wiley   +1 more source

Comparative evaluation of Savanna HSV 1+2/VZV multiplex assay and Simplexa HSV 1&2 and VZV direct kits for rapid molecular detection of HSV-1, HSV-2, and VZV. [PDF]

open access: yesMicrobiol Spectr
Buchan BW   +12 more
europepmc   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik   +3 more
wiley   +1 more source

Assessing the Impact of Female Genital Mutilation/Cutting on Genital Inflammation and Microbiota Among Kenyan Female Sex Workers

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Problem Female genital mutilation/cutting (FGM/C) is harmful to physical, mental, and reproductive health, though the effect of this practice on a woman's HIV susceptibility is poorly understood. Despite the known associations of FGM/C with short‐term vaginal epithelial damage, neither genital inflammation nor the genital microbiome have been ...
James Pollock   +19 more
wiley   +1 more source

Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik   +5 more
wiley   +1 more source

Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma

open access: yesCancer Science, Volume 117, Issue 5, Page 1481-1496, May 2026.
The extent of EBV lytic replication in NPC has not been fully clarified. Our study demonstrated EBV replication and release in NPC and identified a significant association between expression of the late lytic protein gB and poor prognosis. These findings suggest that late lytic gene products may contribute to tumor progression and that gB represents a ...
Shigetaka Komura   +24 more
wiley   +1 more source

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