Host Immune Response Mechanisms Against Herpes Simplex Virus Type 2 Infection. [PDF]
Mei Y, Teng H, Wang J.
europepmc +1 more source
ABSTRACT Objective To quantify the transplacental transfer of aciclovir at an amount equivalent to 2 g of valaciclovir corresponding to the fractionated dosing regimen given four times daily used to reduce congenital cytomegalovirus (CMV) transmission and to treat the CMV‐infected fetus. Design Experimental ex vivo study.
Helyett Ollivier +9 more
wiley +1 more source
Comparative evaluation of Savanna HSV 1+2/VZV multiplex assay and Simplexa HSV 1&2 and VZV direct kits for rapid molecular detection of HSV-1, HSV-2, and VZV. [PDF]
Buchan BW +12 more
europepmc +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Nonlinear fractional stochastic delay modeling and computational analysis of herpes simplex virus type II dynamics. [PDF]
Raza A +3 more
europepmc +1 more source
ABSTRACT Problem Female genital mutilation/cutting (FGM/C) is harmful to physical, mental, and reproductive health, though the effect of this practice on a woman's HIV susceptibility is poorly understood. Despite the known associations of FGM/C with short‐term vaginal epithelial damage, neither genital inflammation nor the genital microbiome have been ...
James Pollock +19 more
wiley +1 more source
The cost-effectiveness of male-partner treatment to prevent recurrence of bacterial vaginosis. [PDF]
Zhang Y +5 more
europepmc +1 more source
Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik +5 more
wiley +1 more source
Adherence to Recommended Immunisation Schedules for Patients With Inflammatory Bowel Disease (IBD) on Biologics: A Retrospective Study at Our Lady's Hospital, Navan, Ireland. [PDF]
Khan A, Shahab M, Anwar MM.
europepmc +1 more source
Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma
The extent of EBV lytic replication in NPC has not been fully clarified. Our study demonstrated EBV replication and release in NPC and identified a significant association between expression of the late lytic protein gB and poor prognosis. These findings suggest that late lytic gene products may contribute to tumor progression and that gB represents a ...
Shigetaka Komura +24 more
wiley +1 more source

