Results 61 to 70 of about 224,366 (294)

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

, 1987
To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Bale, J. F., Giller, R., Koszinowski, Ulrich H., O'Neil, M. E., Perlman, S.   +4 more
core   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Human Immunodeficiency Virus – Acquired Immunodeficiency Syndrome dengan Sarkoma Kaposi

Jurnal Kesehatan Andalas, 2018
Acquired Immunodeficiency Syndrome (AIDS) adalah infeksi yang disebabkan oleh Human Immunodeficiency Virus (HIV) yang menyebabkan suatu penyakit yang menyerang sel-sel kekebalan tubuh.
Riry Febrina Ersha, Armen Ahmad
doaj   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Jahn, Gerhard, Schaffner, Walter, Weber, Frank   +5 more
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Multicentric Castleman’s Disease, Associated with Idiopathic Thrombocytopenic Purpura

Case Reports in Hematology, 2013
The most common cause of a neck mass in young adults is hyperplastic lymphadenopathy consequent to infection and inflammation. Castleman’s disease (CD), an unusual benign lymphoproliferative disorder, infrequently causes neck masses.
Ruchi Sood, Harris C. Taylor, Hamed Daw
doaj   +1 more source

Current status of herpesvirus identification in the oral cavity of HIV-infected children

Revista da Sociedade Brasileira de Medicina Tropical, 2013
INTRODUCTION: Some viruses of the Herpesviridae family are frequently the etiologic agents of oral lesions associated with HIV. The aim of this study was to identify the presence of herpes simplex virus types 1 and 2 (HSV-1, HSV-2), Varicella Zoster
Raquel dos Santos Pinheiro, Dennis de Carvalho Ferreira, Flávia Nóbrega, Norma Suely de Oliveira Santos, Ivete Pomarico Ribeiro de Souza, Gloria Fernanda Barbosa de Araujo Castro   +5 more
doaj   +1 more source

Can the UNAIDS modes of transmission model be improved? A comparison of the original and revised model projections using data from a setting in west Africa. [PDF]

, 2013
OBJECTIVE: The UNAIDS modes of transmission model (MoT) is a user-friendly model, developed to predict the distribution of new HIV infections among different subgroups. The model has been used in 29 countries to guide interventions. However, there is the
Blanchard, James F, Bobrova, Natalia, Foss, Anna M, Heise, Lori, Momah, Amaka, Ogungbemi, Michael K, Prudden, Holly J, Vickerman, Peter, Watts, Charlotte H   +8 more
core   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

Phenoxazine Derivatives Inactivate Human Cytomegalovirus, Herpes Simplex Virus-1, and Herpes Simplex Virus-2 In Vitro

Journal of Pharmacological Sciences, 2008
We examined whether phenoxazine derivatives, 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one (Phx-1), 3-amino-1,4α-dihydro-4α-8-dimethyl-2H-phenoxazine-2-one (Phx-2), and 2-amino-phenoxazine-3-one (Phx-3) may have antiviral activity against ...
Kyoko Hayashi, Toshimitsu Hayashi, Akio Tomoda   +2 more
doaj   +1 more source