Results 91 to 100 of about 172,224 (286)

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

Eye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang, Xiaoyu Song, Fengxin Yang, Huhuifen He, Kun Zhao, Jingjing Qiu, Limei Cui, Qiang Zhang, Limei Liu, Yan Sun   +9 more
wiley   +1 more source

Prevalence of human herpesviruses in biliary fluid and their association with biliary complications after liver transplantation

BMC Gastroenterology, 2019
Background Beta-herpesviruses are common opportunistic pathogens that cause morbidity after liver transplantation (LT). Methods Objective of the study was to evaluate the prevalence and correlation of herpesviruses in bile, blood and liver tissue and to ...
Conrad Rauber, Katja Bartelheimer, Taotao Zhou, Christian Rupp, Paul Schnitzler, Peter Schemmer, Peter Sauer, Karl Heinz Weiss, Daniel Nils Gotthardt   +8 more
doaj   +1 more source

Relationship between human herpesvirus 6 infection and inflammatory bowel disease using novel biomarker

JGH Open, 2023
Objective Inflammatory bowel disease (IBD) is closely related to stress and fatigue. Human herpesvirus 6B (HHV‐6B) is reactivated by stress and fatigue and is associated with IBD.
Satohiro Matsumoto, Yuzo Otaki, Yukio Yoshida, Nobuyuki Kobayashi, Naomi Oka, Hiroyuki Yanagisawa, Kazuhiro Kondo   +6 more
doaj   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

iLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes

mBio, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi’s sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes lytic infection of monocytes in
Kurtis M. Host, Sarah R. Jacobs, John A. West, Zhigang Zhang, Lindsey M. Costantini, Charles M. Stopford, Dirk P. Dittmer, Blossom Damania   +7 more
doaj   +1 more source

Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. [PDF]

, 2019
Cytomegalovirus (CMV) infection causes birth defects and life-threatening complications in immunosuppressed patients. Lack of vaccine and need for more effective drugs have driven widespread ongoing therapeutic development efforts against human CMV (HCMV)
Balogun, Rilwan, Chan, Karen, Dai, Xinghong, Jih, Jonathan, Liu, Fenyong, Liu, Wei, Mei, Ye, Trang, Phong, Yu, Xuekui, Zhou, Z Hong   +9 more
core   +2 more sources

Clinical Significance of Plasma and Peripheral Blood Mononuclear Cell EBV‐DNA in Lymphoma

Journal of Clinical Laboratory Analysis, EarlyView.
Both plasma and PBMC EBV‐DNA can be used to evaluate the prognosis of lymphoma patients. However, plasma EBV‐DNA excels in efficacy monitoring while PBMC EBV‐DNA offers superior prognostic value. Therefore, appropriate sample type could be selected based on clinical scenario.
Lu wang, Guobing Xu, Jianjun Xu, Qingyun Zhang   +3 more
wiley   +1 more source

Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

BMC Molecular and Cell Biology, 2020
Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan   +4 more
doaj   +1 more source

γ-Herpesvirus load as surrogate marker of early death in HIV-1 lymphoma patients submitted to high dose chemotherapy and autologous peripheral blood stem cell transplantation. [PDF]

PLoS ONE, 2015
Autologous stem cell transplantation (ASCT) is a feasible procedure for human immunodeficiency virus-1 (HIV-1) lymphoma patients, whose underlying disease and intrinsic HIV-1- and ASCT-associated immunodeficiency might increase the risk for γ-herpesvirus
Chiara Pratesi, Stefania Zanussi, Rosamaria Tedeschi, Maria Teresa Bortolin, Renato Talamini, Maurizio Rupolo, Chiara Scaini, Giancarlo Basaglia, Matteo Di Maso, Mario Mazzucato, Ernesto Zanet, Umberto Tirelli, Mariagrazia Michieli, Antonino Carbone, Paolo De Paoli   +14 more
doaj   +1 more source

Clinical progress note: Varicella Zoster

Journal of Hospital Medicine, EarlyView.
Abstract Varicella Zoster virus (VZV) is the etiologic agent responsible for varicella and herpes zoster (shingles). Nonimmune children and adults acutely infected with VZV typically experience a vesicular and pruritic rash that progresses from the face and trunk and generalizes to the extremities, accompanied by an oral enanthem along with symptoms of
Sirey Zhang, Adam L. Hersh, T. W. Jones
wiley   +1 more source