Results 121 to 130 of about 2,318,213 (237)

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao   +7 more
wiley   +1 more source

The Clinical Characteristics and Treatment of Patients With Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP‐A): A Retrospective Study of 29 Patients

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
A retrospective analysis of clinical features, treatment, and outcome of 29 patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A). Cerebrospinal fluid (CSF) pressure, CSF nucleated cell count, CSF protein levels, CSF chloride, serum thyroid dysfunction, and abnormal blood cytokine levels correlated with disease severity but ...
Xuewei Yang   +6 more
wiley   +1 more source

A Flavonoid‐Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study investigated the phytochemical profile, cytotoxicity, and anti‐herpetic activity of the hydroethanolic extract from Scoparia dulcis L. aerial parts. Mass spectrometry revealed the presence of 15 compounds. The extract showed low cytotoxicity in Vero cells, maintaining over 80% viability at concentrations up to 250 µg/mL.
Francisco Leandro Medeiros de Lucena Jales   +9 more
wiley   +1 more source

Three Challenging Cases of Autoimmune Encephalitis: A Case‐Series and a Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This manuscript highlights the importance of considering autoimmune encephalitis in patients presenting with multisystem symptoms that cannot be explained by a single neurological condition. Early inclusion of autoimmune encephalitis in the differential diagnosis can help avoid unnecessary treatments and reduce overall healthcare costs.
Mohammad Ali Bahramy   +2 more
wiley   +1 more source

Herpes Simplex Virus Infection With Multiple Cerebral Hemorrhages: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Herpes simplex virus (HSV) infection may trigger rare vascular complications that lead to multiple cerebral hemorrhages. This case emphasizes considering HSV in unexplained cerebral hemorrhage among immunocompromised individuals with systemic symptoms, as timely antiviral treatment effectively improves clinical outcomes.
Zhongzhan Wu   +4 more
wiley   +1 more source

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger   +10 more
wiley   +1 more source

High silent prevalence of human herpesvirus 1 (HSV-1) infection affecting the indigenous reservation of the municipality of Dourados, Central-West Brazil. [PDF]

open access: yesBMC Infect Dis
de Oliveira Bonfim FF   +15 more
europepmc   +1 more source

Inhibition of T-lymphocyte mitogenic responses and effects on cell functions by bovine herpesvirus 1

open access: yesJournal of Virology, 1989
J. Carter   +5 more
semanticscholar   +1 more source

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