Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
Prevalence of Antibodies to Human Herpesvirus 6 in Human Immunodeficiency Virus 1-Seropositive and -Negative Intravenous Drug Addicts [PDF]
, 1989 Hartwig P. Huemer +3 more
openalex +1 more source
Cell Proliferation, EarlyView.CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
Seroprevalencia contra agentes ToRCH en mujeres indígenas en edad fértil, estado Zulia, Venezuela
Biomédica: revista del Instituto Nacional de Salud, 2012 Introducción. El termino ToRCH comprende a los patógenos Toxoplasma gondii, virus de la rubéola, citomegalovirus y virus herpes simple 1 y 2. En mujeres embarazadas expuestas pueden ser causa de abortos y malformaciones congénitas en el neonato ...
Francisca Mercedes Monsalve-Castillo +4 more
doaj +1 more source
European Journal of Clinical Investigation, EarlyView.This systematic review summarizes clinical features, diagnostic strategies and outcomes of paediatric myocarditis associated with Parvovirus B19. Affected children are typically under 3 years old and often present with fulminant symptoms, severe cardiac dysfunction and a high need for ICU‐level support or mechanical circulatory assistance.
Giacomo Veronese +5 more
wiley +1 more source
Management of alpha-herpesvirus infection following kidney transplantation: Our experience (7 cases)
Transplantation Reports, 2020 Background: Kidney transplantation is the definitive treatment for patients with end-stage kidney diseases. Quality of life and longevity following transplantation are nearly equal to those of healthy individuals.
Hirofumi Uehara +8 more
doaj
Pathogenic, Molecular, and Immunological Properties of a Virus Associated with Sea Turtle Fibropapillomatosis. Phase II : Viral Pathogenesis and Development of Diagnostic Assays [PDF]
, 2000 Research conducted under this RWO from July 1, 1997 through June 30, 2000 has provided important new information about the pathogenesis, virology, and immunology of marine turtle fibropapillomatosis. In particular, we have provided strong evidence for
Bjorndal, Karen A. +8 more
core
In vitro susceptibility of T lymphocytes from chimpanzees (Pan troglodytes) to human herpesvirus 6 (HHV-6): a potential animal model to study the interaction between HHV-6 and human immunodeficiency virus type 1 in vivo [PDF]
, 1990 Paolo Lusso +3 more
openalex +1 more source
Equine Veterinary Education, EarlyView.Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan +3 more
wiley +1 more source
A guide to heat shock factors as multifunctional transcriptional regulators
The FEBS Journal, EarlyView.The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka +3 more
wiley +1 more source