Results 171 to 180 of about 172,224 (286)

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, Volume 35, Issue 5, September 2025.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Latency-Associated Nuclear Antigen Encoded by Kaposi's Sarcoma-Associated Herpesvirus Interacts with Tat and Activates the Long Terminal Repeat of Human Immunodeficiency Virus Type 1 in Human Cells [PDF]

, 2001
Teresa S. Hyun, Chitra Subramanian, Murray A. Cotter, Robert A. Thomas, Erle S. Robertson   +4 more
openalex   +1 more source

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1717-1722, August 2025.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source

Reactivities of Human Sera with Human Herpesvirus-8-Infected BCBL-1 Cells and Identification of HHV-8-Specific Proteins and Glycoproteins and the Encoding cDNAs

, 1998
Bala Chandran, Marilyn S. Smith, David M. Koelle, Lawrence Corey, Rebecca T. Horvat, Elliot Goldstein   +5 more
openalex   +1 more source

Close but Distinct Regions of Human Herpesvirus 8 Latency-Associated Nuclear Antigen 1 Are Responsible for Nuclear Targeting and Binding to Human Mitotic Chromosomes [PDF]

, 2001
Tristan Piolot, Marc Tramier, Maïté Coppey‐Moisan, Jean‐Claude Nicolas, Vincent Maréchal   +4 more
openalex   +1 more source

Physics of Protein Aggregation in Normal and Accelerated Brain Aging

BioEssays, Volume 47, Issue 8, August 2025.
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay, Andrea Sturchio, Alberto Imarisio, Emily J. Hill, Brady Williamson, Kora Montemagno, Christian Hoffmann, Hugo Le Roy, Dragomir Milovanovic, Fredric P. Manfredsson   +9 more
wiley   +1 more source

Elucidation of the Hemostatic and Anti‐Inflammatory Effects of Walnut Shell Ethanol Extract by Network Pharmacology and Experimental Verification

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Forty‐five components of WSEE were identified by UPLC‐Q‐TOF‐MS. The main targets of WSEE were PTPN2, ADRB2, LTA4H, and so on in wound healing. WSEE has an anti‐inflammatory effect in LPS‐stimulated RAW264.7 cells, procoagulant activity in vitro, and shortens hemostasis time in vivo.
Ying He, Wenhui Zhao, Yanting Sun, Lei Ma, Censhu Li, Xueying Zheng, Zeguo Feng, Hui Guo, Liguo Qin, Yali Zhang   +9 more
wiley   +1 more source

A New Next‐Generation Sequencing Approach in Human Cytomegalovirus for the Identification of Antiviral Resistance Mutations and Genotypic Classification

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT This study introduces a new procedure for antiviral resistance analysis and genetic classification of human cytomegalovirus (HCMV) using next‐generation sequencing (NGS) adapted to existing methodologies, aiming for more targets due to the recent use of new antivirals. It expands the classical investigation of mutations in UL54 and UL97 genes,
Maria Arnedo‐Muñoz, Ignasi Prats‐Méndez, Alejandra Gónzalez‐Sánchez, Maria Carmen Martín, Ariadna Rando‐Segura, Ibai Los Arcos, Patricia Nadal‐Barón, Narcís Saubi, Natalia Mendoza‐Palomar, Marta Bernat‐Sole, Adaia Albasanz‐Puig, Maria Piñana, Cristina Andrés, Susana Melendo‐Pérez, Nieves Larrosa, Andrés Antón, Juliana Esperalba   +16 more
wiley   +1 more source

Interleukin 1β induces expression of human herpesvirus 8 encoded genes in BCBL-1 cells

, 1999
Yimin Yu, Florence Roan, Margaret K. Offermann   +2 more
openalex   +1 more source

Novel Cereblon‐Binding Immunomodulators Have Increased Potency Against Gammaherpesvirus‐ Associated Lymphomas In Vitro

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Primary effusion lymphoma (PEL), which is caused by Kaposi sarcoma herpesvirus (KSHV), and Burkitt lymphoma (BL), a subset of which are associated with Epstein‐Barr virus (EBV), are aggressive non‐Hodgkin's lymphomas. Both have relatively poor survival compared to other lymphomas. Cereblon‐binding immunomodulators (CBIs), such as pomalidomide (
Prabha Shrestha, Emma N. Treco, David A. Davis, Robert Yarchoan   +3 more
wiley   +1 more source