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Interference between human herpesvirus 7 and HIV-1 in mononuclear phagocytes

The Journal of Immunology, 1996
Abstract Human herpesvirus 7 (HHV-7) uses CD4 as a cellular membrane receptor and thereby interferes with infection of CD4+ T cells by HIV-1. We studied the interactions between HHV-7 and a macrophage-tropic HIV-1 isolate (HIV-1BaL) in terminally differentiated human peripheral blood monocyte-derived macrophages, another critical target ...
CROWLEY RW   +5 more
openaire   +3 more sources

Human Herpesvirus 8 (Kaposi's Sarcoma–Associated Herpesvirus) Infection in Men Receiving Treatment for HIV-1 Infection

JAIDS Journal of Acquired Immune Deficiency Syndromes, 1999
To determine the prevalence of human herpesvirus 8 (HHV-8) infection in men treated for HIV-1 infection in Denver, Colorado.Cross-sectional analysisBlood samples were obtained from 216 HIV-1-infected men. Antibody to latency-associated nuclear antigen (LANA) was detected by an immunofluorescent assay and the presence of HHV-8 in peripheral blood ...
Xing-Quan Zhang   +4 more
openaire   +3 more sources

Inhibitory Effect of Alloferons in Combination with Human Lymphocytes on Human Herpesvirus 1 (HHV-1) Replication In Vitro

International Journal of Peptide Research and Therapeutics, 2015
Over the past two decades there has been intense study of compounds from vertebrates, microorganisms, plants, mushrooms, marine sponges, worms, etc. as well as insects in terms of their antiviral activity. Insects produce a variety of biologically active peptides. One of them is alloferon. The in vitro and in vivo experiments demonstrate that synthetic
Grażyna Młynarczyk   +3 more
openaire   +2 more sources

Reciprocal in vitro interactions between human herpesvirus-6 and HIV-1 Tat

AIDS, 1991
The transactivation induced by human herpesvirus 6 (HHV-6) on the HIV-1 promoter was studied both in the presence and in the absence of the retroviral transactivator protein (Tat) constitutively expressed in Jurkat cells. Jurkat-tat cells were infected with HHV-6, transfected with a plasmid containing HIV-1 long terminal repeat (LTR)/chloramphenicol ...
DI LUCA, Dario   +6 more
openaire   +5 more sources

Effects of the anti-cancer agent etoposide on human herpesvirus 1 replication in vitro

Research in Virology, 1989
The anti-human herpesvirus type 1 (herpes simplex virus 1; HSV1) activity of etoposide (VP-16-213, a semi-synthetic derivative of epipodophyllotoxin) was investigated in vitro. Etoposide (but not the proprietary solvent in which the compound is usually formulated) demonstrated a significant antiviral action, probably through an effect on virus ...
Lewis, A. G.   +4 more
openaire   +3 more sources

Induction of CD4 and susceptibility to HIV-1 infection in human CD8+ T lymphocytes by human herpesvirus 6

Nature, 1991
During intrathymic T-cell ontogenesis, functionally competent CD3+CD4+CD8- and CD3+CD4-CD8+ T lymphocytes develop from immature CD4-CD8- thymocytes after transiently acquiring a double-positive CD4+CD8+ phenotype. The partition between CD4+CD8- and CD4-CD8+ T cells is generally considered to be irreversible, although a small percentage of circulating ...
Andrea De Maria   +6 more
openaire   +3 more sources

Chapter 1 The discovery of human herpesvirus type 6

1992
Publisher Summary This chapter presents the events that led to the discovery of human herpesvirus type 6 (HHV-6). The period of 1984–1986 was perhaps one of the most exciting periods in biomedicine because of the epidemic of acquired immune deficiency syndrome (AIDS).
openaire   +2 more sources

Presence of Human Herpesvirus 6B in the Pancreas of Subjects With and Without Type 1 Diabetes

Pancreas, 2017
Objectives The aims of this study were to investigate the presence of human herpesvirus 6 (HHV6) A and B in human pancreata and to search for signs of active infection in this organ of subjects with and without type 1 diabetes (T1D).
Oskar Skog, Maja Ericsson
openaire   +2 more sources

Human herpesvirus‐6 reactivation in a longitudinal study of two HIV‐1 infected patients

Journal of Medical Virology, 1997
After primary infection, human herpesvirus-6 (HHV-6) persists in latent form and can be reactivated in immunocompromised subjects. A longitudinal study of HHV-6 infection was carried out in two HIV-1 seropositive patients to provide in vivo evidence of HHV-6 reactivation.
G Forastieri   +12 more
openaire   +4 more sources

Seroprevalence of human herpesvirus 8 in human immunodeficiency virus 1-positive and human immunodeficiency virus 1-negative populations in Japan

Journal of Medical Virology, 1999
To determine the seroprevalence of human herpesvirus 8 (HHV8) among human immunodeficiency virus 1 (HIV-1)-positive (HIV-1+) and HIV-1-negative (HIV-1-) populations in Japan, 276 HIV-1+ patients and 1,000 HIV-1- blood donors were enrolled in this study.
Tetsuya Nakamura   +9 more
openaire   +2 more sources

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