Results 81 to 90 of about 172,650 (280)
Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation
Viruses, 2021 Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases
Joachim Denner
doaj +1 more source
Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]
, 2013 Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
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Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]
, 2019 Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid +3 more
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Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Biotechnology Progress, EarlyView.Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao +5 more
wiley +1 more source
Animal models of human herpesvirus infection
Animal Models and Experimental MedicineHuman herpesvirus, a specific group within the herpesvirus family, is responsible for a variety of human diseases. These viruses can infect humans and other vertebrates, primarily targeting the skin, mucous membranes, and neural tissues, thereby ...
Ziqing Jia +3 more
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Bilateral Acute Retinal Necrosis and Encephalomalacia Due to Herpes Simplex Virus Infection in a Premature Infant [PDF]
Neonatal Medicine, 2019 Herpes simplex virus (HSV) is a common pathogen, that causes a broad spectrum of diseases, ranging from minor skin infections to severe encephalitis and widespread infections.
Mi Hye Bae +9 more
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ChemBioChem, Accepted Article.Fibroblast growth factor 2 (FGF2) regulates signal transduction by forming complexes with its receptors, FGF receptors (FGFRs), and heparan sulfate (HS), playing a crucial role in biological systems. Although HS has been suggested to modulate FGF/FGFR signaling as a co‐receptor, multiple hypotheses exist regarding how HS affects FGF/FGFR signaling, and
Yuga Okada +5 more
wiley +1 more source
The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]
, 1985 The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael +9 more
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ChemMedChem, EarlyView.Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Matteo Lusardi +9 more
wiley +1 more source