Results 141 to 150 of about 25,174,333 (247)
Background. Chronic persistence of lymphotropic human herpesviruses (HHV) serves as a potent driver of systemic immune dysfunction and oxidative stress, potentially initiating or exacerbating autoimmune endocrine disorders.
Ye.V. Sydorenko, O.K. Duda, A.P. Golub
doaj +1 more source
When to consider an inborn error of immunity: clues for physicians
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Background. Human herpesvirus 6 belongs to betaherpesviruses. This is a lymphotropic virus which is widely spread in a population. The most frequent way of virus transmission is by saliva.
Jožica Marin
core
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo +7 more
wiley +1 more source
リンパ増殖性疾患とHuman herpesvirus 6 (HHV-6)の関連性のPCR法による検討(第1報)
Human herpesvirus 6 (HHV-6)は1986年に新たに発見されたウイルスであり様々な疾患との関連性が示唆されている。HHV-6とリンパ増殖性疾患との関連性を検討するために、このウイルスDNAに特異的なプライマーを作製し、それを用いたPCR法で、患者より採取した末梢血およびリンパ組織中のHHV-6ゲノムの検出を行った。 8名の健常人、40例のリンパ増殖性疾患、1例の慢性骨髄性白血病について検討したが、今回施行した49検体では、HHV-6は検出されず、HHV ...
サダ, エイジ +15 more
core +1 more source
Angiosarcoma Presenting as a Chronic Non‐Healing Lower Extremity Ulcer in Lymphoedema: A Challenge
ABSTRACT Cutaneous angiosarcoma is a rare and aggressive malignancy that may arise in chronic lymphoedema. Its presentation as a non‐healing ulcer can lead to delayed diagnosis. We describe an atypical case of angiosarcoma presenting as a chronic lower extremity ulcer in the setting of chronic lymphoedema and to highlight the importance of early biopsy.
Megan Koch +3 more
wiley +1 more source
ABSTRACT The 2019 International Pediatric Transplant Association (IPTA) consensus conference assessed available evidence and developed recommendations for various aspects of care relating to post‐transplant lymphoproliferative disorders (PTLD) after solid organ transplantation in children.
Michael Green +7 more
wiley +1 more source
Human herpesvirus (HHV) 8 or Kaposi’s sarcoma associated herpesvirus (KSHV) is the newest member of the HHV family, discovered almost a decade ago in Kaposi’s sarcoma (KS) tissue (1–3).
Mitchell, Charles D, Wood, Charles
core +1 more source
Background Herpesviruses are DNA viruses that establish lifelong latent infections in their hosts. During host-virus co-evolution, several members of the herpesvirus family acquired genes reminiscent of human chemokines and their G protein-coupled ...
Qianqian Kong +6 more
doaj +1 more source
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source

