Results 51 to 60 of about 641,508 (253)

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D, Dowd, JB, Fletcher, H, Hayward, SE, Nellums, LB, Wurie, F   +5 more
core   +2 more sources

Encephalitis associated with Zika virus infection and reactivation of the varicella-zoster virus in a Brazilian child

Revista da Sociedade Brasileira de Medicina Tropical
We report a case of encephalitis associated with Zika virus infection and reactivation of varicella-zoster virus in the central nervous system of a Brazilian child.
Marcelo Adriano da Cunha e Silva Vieira, Alzira Almeida de Sousa Castro, Daniele Freitas Henriques, Eliana Vieira Pinto da Silva, Fernando Neto Tavares, Lívia Carício Martins, Lucas Melo Guimarães, Talita Antonia Furtado Monteiro, Raimunda do Socorro da Silva Azevedo, Ana Cecíclia Ribeiro Cruz, Pedro Fernando da Costa Vasconcelos   +10 more
doaj   +1 more source

Marshall’s syndrome in the practice of infection disease doctor and pediatrician (сlinical case)

Журнал инфектологии, 2020
On the basis of literary sources, modern ideas about Marshall syndrome in children are given, as well as the main clinical and laboratory criteria for the diagnosis of this syndrome. A clinical case of Marshall syndrome in a boy 3 years 6 months infected
I. V. Babachenko, N. S. Tian, M. A. Ivanova, E. V. Sharipova, T. L. Belikova   +4 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. [PDF]

, 2020
Molecular mechanisms of Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation have been studied primarily by measuring the total or average activity of an infected cell population, which often consists of a mixture of both nonresponding and ...
Campbell, Mel, Chuang, Frank, Guevara-Plunkett, Sara, Izumiya, Chie, Izumiya, Yoshihiro, Kumar, Ashish, Luxardi, Guillaume, Lyu, Yuanzhi, Nakajima, Ken-Ichi, Soulika, Athena, Wang, Kang-Hsin   +10 more
core  

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara, Faggioni, Alberto, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Granato, Marisa, Romeo, Maria Anele, Santarelli, Roberta, Tiano, Mariangela Sara   +7 more
core   +2 more sources

Elevated iNOS and 3′-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model

Tumour Virus Research, 2023
Kaposi's Sarcoma (KS) is a heterogenous, multifocal vascular malignancy caused by the human herpesvirus 8 (HHV8), also known as Kaposi's Sarcoma-Associated Herpesvirus (KSHV). Here, we show that KS lesions express iNOS/NOS2 broadly throughout KS lesions,
Olga Vladimirova, Samantha Soldan, Chenhe Su, Andrew Kossenkov, Owen Ngalamika, For Yue Tso, John T. West, Charles Wood, Paul M. Lieberman   +8 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source